Vaccine Research Laboratory of Professor Mario A. Monteiro



Department of Chemistry, University of Guelph, Guelph, Ontario, CANADA




Recipient of the University of Guelph Inaugural Innovation Award


Dr. Silvia Borrelli joins our research group


Speaker at the 2016 Canadian Chemistry Conference


Speaker at the 2016 US National Foundation for Infectious Diseases Conference


Activity for high school students based on our research (developed by Kristina Salciccioli)


Voted one of the most influential people in vaccines


Winner of the 2015 Professional Excellence Award from the Federation of Portuguese-Canadian Business and Professionals


Diarrhea vaccine enters Phase 1 human clinical trial


Clostridium difficile vaccine licensed by pharmaceutical company


The Bug Doctor ACCN article by Roberta Staley





A vaccine against the colorectal cancer pathogen, Fusobacterium nucleatum

Development of a Fusobacterium nucleatum polysaccharide-based vaccine


Anti-diarrhea vaccine (anti-Campylobacter jejuni)

Design of Campylobacter jejuni vaccine

Review of Campylobacter polysaccharide vaccines

Research publication about anti-diarrhea vaccine

news article


Clostridium difficile vaccine

Book chapter describing the synthesis of a Clostridium difficile vaccine

Vaccination with Clostridium difficile PS-II polysaccharide antigen induced protection in mice

Review about Clostridium difficile carbohydrate-based vaccines

Discovery of Clostridium difficile capsule polysaccharides PS-I and PS-II

Patent divulging water-soluble polysaccharides (PS-I and PS-II) and phenol-soluble polysaccharide (PS-III) of Clostridium difficile

Discovery of glucan in Clostridium difficile spores and immunogenicity of PS-II

Synthesis and immunogenicity of Clostridium difficile PS-II conjugate vaccines

Synthesis of the repeating unit of Clostridium difficile polysaccharide PS-I and detection of PS-I antibodies


Development of diagnostics to detect autism-associated gut bacteria

Key points and goals

Discovery of Clostridium bolteae immunogenic polysaccharide

Gut bacteria may hold key to some autism-related symptoms

A vaccine target for Clostridium bolteae, an autism-associated bacterium


Gastric cancer vaccine (anti-Helicobacter pylori)

Review of Helicobacter pylori polysaccharides

Research publication about gastric cancer vaccine (Helicobacter pylori)


Otitis media vaccine (middle-ear infection vaccine)

Discovery of Alloicoccus otitidis polysaccharides

Alloiococcus otitidis vaccine patent (otitis media)


Research article about new conjugation strategy for vaccine development and that yields more immunogenic conjugate vaccines


Studies about new Ruthenium Chloride complexes and the composition of the coordination precursor Ruthenium Blue


Click here to familiarize yourself with our research or watch videos 1, 2, and 3







List of our publications on PubMed and Google Scholar

Professional Experience


Editorial Board Member of Carbohydrate Research




Join Our Research Team

Please send me ( your complete curriculum vitae and two reference letters or contacts.

If you do not have any publications and are applying for a Ph.D. position, you must submit with your application a copy of your M.Sc. thesis.

Please note that I will reply only if a suitable position is available.

Potential graduate students have to be accepted by the Guelph-Waterloo Centre for Graduate Work in Chemistry and Biochemistry.




►New students must complete Workplace Hazardous Materials Information System (WHMIS) training and the Safety Training Course, and read the laboratory safety guidelines before starting laboratory work in laboratory.

Safety glasses and lab coats are required at all times when visiting or working in laboratory.