Peter Podobed
Supervisor: Dr. Tami Martino

Committee:
Dr. Tami A. Martino (advisor)
Dr. Glen W. Pyle
Dr. Gordon M. Kirby
Dr. Jeremy A. Simpson

Academic Background:
Honours Bachelor of Science, University of Toronto (09/2005 - 05/2009)
Masters of Science (M.Sc), Department of Biomedical sciences, University of Guelph (09/2009 - 10/2010 reclassified to Ph.D)
Doctor of Philosophy (Ph.D), Department of Biomedical sciences, University of Guelph (09/2010 - 08/2014).

Awards:

Memberships:


Research Interests:


Thesis Topic:
The Cardiac Circadian Proteome and Transcriptome: a Novel Paradigm Characterizing Cardiovascular Health and Disease.

Conferences Attended:
Heart Failure in 2011: Thinking Beyond Traditional Management Strategies
University of Western Ontario, Conron Hall Wednesday June 8, 2011 Sponsored by Servier Canada

"Circadian orchestration of the cardiovascular proteome. A novel paradigm characterizing cardiovascular physiology in health and disease." Young Investigators forum (CIHR), Vancouver, BC, May 5-7, 2010.

"Tumor necrosis factor-alpha produced in cardiomyocytes mediates a predominant myocardial inflammatory response to stretch in early volume overload", Cardiovascular journal club, University of Guelph, January 28, 2010.

"Circadian proteome in normal heart and in heart disease." Departmental seminar, Biomedical Sciences, University of Guelph, June 16, 2010.

"Cyclin expression in mouse retinoblastoma." Research day, University Health Network, August 21, 2008.

Publications:
P.S. Podobed, W. Glen Pyle, , S. Ackloo, F.J. Alibhai, E. Tsimakouridze, W.F. Ratcliffe, A. Mackay, J. Simpson, G. Kirby, M. Young, T.A. Martino. The Day/Night Proteome in the Murine Heart. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 2014.
P. S. Podobed, F.J. Alibhai, C.W. Chow, T. A. Martino (2014) Circadian Regulation of Myocardial Sarcomeric Titin-cap (Tcap, Telethonin): Identification of Cardiac Clock-Controlled Genes Using Open Access Bioinformatics Data. Plos One 9:e104907.
Podobed P, Kirby G, Martino T.A. (2012). Circadian proteomics and its unique advantage for discovery of biomarkers of heart disease. In TK Man, RJ Flores (Eds.) "Proteomics. Human Diseases and Protein Functions", pp. 65-88. InTech.
Tsimakouridze E.V., Straume M, Podobed P, Chin H, LaMarre J, Johnson R, Antenos M, Kirby G, Mackay A, Huether P, Simpson J, Sole M, Gadal G, Martino T.A. (2012). Chronomics of Pressure Overload Induced Cardiac Hypertrophy in Mice Reveals Altered Day/Night Gene Expression in Heart Disease. Chronobiology International, 7: In Press.
Martino T.A, Tata N, Simpson J, Vanderlaan R, Dawood F, Kabir G, Khaper N, Cifelli C, Podobed P, Liu P, Husain M, Heximer S, Backx P, and Sole M. (2011). The primary benefits of Angiotensin-converting enzyme inhibition on cardiac remodeling occur during sleep time in murine pressure overload hypertrophy. J Am Coll Cardiol 57(20): 2020-2028.

Book chapter:
Podobed P.S., Kirby G.M., Martino T.A. (2012). Circadian Proteomics and Its Unique Advantage for Discovery of Biomarkers of Heart Disease. In T.K. Man and R.J. Flores (Eds.) Proteomics, Book 1, InTech. ISBN 978-953-307-832-8.

Abstracts:
Podobed P, Pyle WG, Ackloo S, Alibhai FJ, Tsimakouridze E, Young ME, Martino T. Extensive day-night variations of mitochondrial proteins in the murine heart. Society for Heart and Vascular Metabolism, Cambridge, MD, USA, Sept.29-Oct.2, 2013.
P.S. Podobed, W.G. Pyle, M. Young, S. Ackloo, E.V. Tsimakouridze, F.J. Alibhai, G.M. Kirby, T.A. Martino. Discovery of diurnal cardiac proteome and its role in normal cardiac physiology. Canadian Society for Chronobiology conference, Toronto, May 24 - 26, 2013.
P.S. Podobed, G.M. Kirby, S. Ackloo, F.H. Yang, A. Mackay, P. Huether, M.E. Young, J.A. Simpson, W.G. Pyle, T.A. Martino. Discovery of the Circadian Cardiac Proteome by Two-Dimensional Difference in Gel Electrophoresis and Mass Spectrometry. Canadian National Proteomics Network, 4th Annual Symposium, Toronto, 2012.
P.S. Podobed, M.R. Bennardo, W.G. Pyle, P.H. Backx, P. Huether, A. Mackay, M.J. Sole, R. Johnson, G.M. Kirby, J.A. Simpson, T.A. Martino. Circadian orchestration of the cardiovascular proteome. A novel paradigm characterizing cardiovascular physiology in health and disease. Canadian Institute of Health Research (CIHR) Young Investigators Forum (YIF), Vancouver, British Columbia, May 5 -7, 2010.
M.R. Bennardo, P.S. Podobed, W.G. Pyle, P.H. Backx, P. Huether, A. Mackay, M.J. Sole, R. Johnson, G.M. Kirby, J.A. Simpson, T.A. Martino. The circadian proteome of the heart: Basic molecular differences in response to myocardial infarctions that occur in the day versus night. CIHR, Young Investigators Forum. Vancouver, British Columbia. May 5 -7, 2010
Tsimakouridze Elena, Podobed Peter, Bennardo Michael, Johnson Ron, LaMarre Jonathan, Sole Michael, Straume Martin, Martino Tami. Diurnal Rhythms in Gene Expression as Critical Determinants of Cardiovascular Disease; A Novel Platform for Biomarker Discovery.

Other Tidbits:
Interests: networking, learning, teaching
Sports: tennis, hockey
Hobbies: photography, travelling