University of Guelph
50 Stone Road East
Guelph, Ontario, Canada
N1G 2W1

The Department of Human Health & Nutritional Sciences
Animal Science/Nutrition Building
519-824-4120 x56171
Fax: 519-763-5902
© 2013 University of Guelph - Content provided on this website is for information purposes only and is subject to change without notice.

Dr. Marica Bakovic



B.Sc. - Belgrade
M.Sc. - Belgrade
Ph.D. - Alberta


Regulation of genes involved in choline transport and phospholipid metabolism; nutrient transporters and kinetics of membrane transport; molecular and cell biology of lipids; the effect of nutrients on protein synthesis and gene expression. Nutritional genomics (nutrigenomics) of risk factors for cardiovascular disease and insulin resistance

Selected Publications

Pavlovic Z, Zhu L, Pereira L, Singh RK, Cornell RB,
Bakovic M
. Isoform-specific and PKC mediated regulation of CTP: phosphoethanolamine cytidylyltransferase phosphorylation. J Biol Chem. 2014. [Epub ahead of print].

Schenkel LC,
Bakovic M
. Formation and regulation of mitochondrial membranes. Int J Cell Biol. 2014. [Epub ahead of print].

Gohil VM, Zhu L, Baker CD, Cracan V, Yaseen A, Jain M, Clish CB, Brookes PS,
Bakovic M
, Mootha VK. Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism. J Biol Chem. 2013; 288(49):35387-95.

Verbrugghe A,
Bakovic M
. Peculiarities of one-carbon metabolism in the strict carnivorous cat and the role in feline hepatic lipidosis. Nutrients. 2013; 5(7):2811-35.

Pavlovic Z,
Bakovic M
. Regulation of Phosphatidylethanolamine Homeostasis - The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2). Int J Mol Sci. 2013; 14(2):2529-50.

Singh RK, Fullerton DM, Vine D,
Bakovic, M
. Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase (Pcyt2) deficient mice. J Lipid Res. 2012; 53, 1811-1822.

Duric M, Servanesen S and
Bakovic M
. Phosphatidylcholine Functional Foods and Nutraceuticals: A Potential Approach to Prevent Non-alcoholic fatty liver disease. European J Lipid SciTechnology. 2012; 114:389-398. 

Zhu L,
Bakovic M
. Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP: ethanolaminephosphate cytidylyltransferase-Pcyt2 activity. Biochem Cell Biol. 2012; 90(2):188-99.

Pereira L, Girardi JP,
Bakovic M
. Forms, cross-talks, and the role of phospholipid biosynthesis in autophagy. Int. J Cell Biol. 2012:931956.

Bakovic M
, Michel V. Eds (2012). Hot Topic Mini-Review Edition on Choline In:"Central Nervous System Agents in Medicinal Chemistry", Bentham Science Publishers. ISSN: 1871-5249.

Michel V,
Bakovic M
.  The ubiquitous choline transporter SLC44A1. Cent Nerv Syst Agents Med Chem. 2012; 12(2):70-81.

Bakovic M
. Different systemic and peripheral ghrelin responses in metabolic disorders. J Pediatr Biochem. 2012; 2(2):61-2.

Girardi JP, Pereira L,
Bakovic M
. De novo synthesis of phospholipids is coupled with autophagosome formation. Med Hypotheses. 2011; 77(6):1083-7.


HHNS*6440 Nutrition and Gene Expression
NUTR*4360 Current Issues in Nutrigenomics

Graduate Students

A. Stefanson (PhD Student)
A. Taylor (PhD Student)
A. Ardila (MSc Student)
A. D'Silva (MSc Student)
J. Ichhpuniani (MSc Student)

Post-Doctoral Fellows

R. Singh
A. Tie

Office:    ANNU 346
Ext:         53764
Lab:       ANNU 309
Ext:         56717
Photo of Dr. Marica Bakovic