Graduate Defences. Department of Molecular and Cellular Biology



2017

  • Carlucci, Christian - PHD.MCB - March 2, 2017
    (Advisor: E. Allen-Vercoe)
    Examining the effects of defined microbial ecosystems on Clostridioides difficile growth and virulence
  • Herlihey, Francesca - PHD.MCB - January 24, 2017
    (Advisor: A. Clarke)
    Biochemical Characterization of the Activity and Control of the Autolysins Involved in Flagella Assembly in Gram-Negative Bacteria
  • Liu, Haidun - MSC.MCB - January 20, 2017
    (Advisor: J. Dawson)
    How do regulated thin filaments with hypertrophic cardiomyopathy-linked α-cardiac actin affect actomyosin interactions?
  • Secord, Nathaniel - MSC.MCB - January 12, 2017
    (Advisor: S. Rothstein)
    Exploring the potential of AtENOD93 and A. thaliana as a model system to study ENOD93-like proteins

2016

  • Czaniecki, Christopher - MSC.MCB.NEUR - December 12, 2016
    (Advisor: S. Ryan)
    Innate neurite deficits in hESC-derived Parkinson’s neurons are rescued by NRF2-mediated activation of the anti-oxidant response
  • Coumoundouros, Chelsea - MSC.MCB - November 29, 2016
    (Advisor: J. Wood)
    Investigating the Oligomeric State of Osmoregulatory Transporter ProP of Escherichia coli and its Functional Consequences
  • Watt, Samantha - MSC.MCB - October 18, 2016
    (Advisor: R. Mullen)
    Arabidopsis AT3G11620 is an evolutionarily conserved protein involved in facilitating the intracellular distribution of lipid droplets
  • Poole, Amanda - MSC.MCB - September 13, 2016
    (Advisor: R. Merrill)
    Kinetic characterization of VopT, a mono-ADP-ribosyltransferase toxin from Vibrio parahaemolyticus
  • Varga, Joseph - MSC.MCB - August 31, 2016
    (Advisor: J. Uniacke)
    Cancer cells exploit eIF4E2-directed translation to enhance their proliferation, migration and invasion
  • Charles, Sherise - MSC.MCB - August 30, 2016
    (Advisor: C. Khursigara)
    The proteomic response of the probiotic Pediococcus acidilactici R1001 after exposure to the cell-free supernatant of the pathogen Listeria monocytogenes ATCC 7644
  • McNeilly, Rachael - MSC.MCB - August 23, 2016
    (Advisor: N. Jones)
    Investigating intracellular SNARE-mediated trafficking of the kidney slit diaphragm protein nephrin
  • Weiss, Alexander - MSC.MCB - August 22, 2016
    (Advisor: T. Van Raay)
    Defining Wnt activity and Nkd1 function in mammalian cell lines IEC-18 and HEK293
  • Reynolds, Kathryn - MSC.MCB - August 19, 2016
    (Advisor: J. Vessey)
    The RNA-binding protein Musashi2 regulates asymmetric neural precursor cell divisions of the developing cerebral cortex
  • Gonzalez, Karen - MSC.MCB - June 22, 2016
    (Advisor: J. Wood)
    The Impacts of ProP putative interactors on the localization and activity of the transporter ProP, and on Escherichia coli phenotype
  • Abbasi, Sanna - MSC.MCB - June 7, 2016
    (Advisor: J. Yankulov)
    The impact of subtelomeric DNA on epigenetic switching in Saccharomyces cerevisiae
  • Martin, Will - MSC.MCB - May 31, 2016
    (Advisor: L. Mutharia)
    The isolation and proteomic analysis of Mycobacterium avium subspecies paratuberculosis secreted membrane vesicles 
  • Xu, Zhenhua - PHD.MCB - May 16, 2016
    (Advisor: S. Rothstein)
    The role of anthocyanins and the GATA transcription factors GNC and CGA1 in the plant response to stress
  • Mazurkewich, Scott - PHD.MCB - May 4, 2016
    (Advisor: S. Seah)
    Characterization of the 4-carboxy-2-hydroxymuconate hydratase and the 4-carboxy-4-hydroxy-2-oxoadipate / 4-hydroxy-4-methyl-2-oxoglutarate aldolase from Pseudomonas putida
  • Carlow, Chevonne - PHD.MCB - April 28, 2016
    (Advisor: A. Nassuth)
    Analysis of the Vitis CBF genes and their potential roles in the both the CBF and stomatal development pathways
  • Mundia, Maureen - PHD.MCB - April 27, 2016
    (Advisor: M. Baker)
    Analysis of the genetic requirements for Rad51-mediated 3' polymerization during DNA repair by homologous recombination
  • Albeely (Mohamed), Abdalla - MSC.MCB - April 26, 2016
    (Co-Advisors: R. Nazar/A.Bendall)
    Termination of Ribosomal RNA Transcript by RNA polymerase I in Schizosaccharomyces pombe
  • Wills, Melanie - PHD.MCB - April 12, 2016
    (Advisor: N. Jones)
    Decoding Shc deviance: Evidence of novel roles for the phosphotyrosine adaptor ShcD in Epidermal Growth Factor Receptor (EGFR) signalling and dynamics
  • Faultless, JW Trent - MSC.MCB - April 7, 2016
    (Advisor: A. Nassuth)
    Protein domains of Vitis CBF1 and translational regulation of cold-induced genes via codon usage
  • Castroverde, Christian Danve M. - PHD.MCB - March 31, 2016
    (Advisors: J. Mathur and J. Robb)
    Molecular biology of the tomato Ve gene family
  • Cochrane, Kyla - PHD.MCB - February 26, 2016
    (Advisor: E. Allen-Vercoe)
    Elucidating potential virulence factors in Fusobacterium nucleatum
  • Taylor, Véronique - PHD.MCB - February 19, 2016
    (Advisor: J. Lam)
    Molecular and biochemical investigation of mechanisms that propel O-antigen diversity in Pseudomonas aeruginosa
  • Blake, Katherine - MSC.MCB - January 28, 2016
    (Advisors: J. Uniacke and G. Bag)
    An investigation of the non-redundant functions of PABPC4 via protein-protein interactions and PABP-depletion studies
  • Pasula, Daniel - MSC.MCB - January 6, 2016
    (Advisor: T. Van Raay)
    Investigating the role of Axin2 in the regulation of the Wnt signaling pathway in early zebrafish development
  • Udaskin, Molly - MSC.MCB - January 5, 2016
    (Advisor: B. Meng)
    Investigation into the proteolytic processing and localization of the replicase polyprotein of Grapevine rupestris stem pitting-associated virus

2015

  • Kell, Elisabeth - MSC.MCB - December 22, 2015
    (Advisor: C. Whitfield)
    Characterizing properties of bacterial outer membrane polysaccharide export (OPX) proteins
  • Toh, Michael - PHD.MCB - December 10, 2015
    (Advisor: E. Allen-Vercoe / T. VanRaay)
    Zebrafish as a novel animal model for evaluating the human gastrointestinal microbiota in autism spectrum disorder
  • Wozny, Michael - MSC.MCB - December 9, 2015
    (Advisor: J. Mathur)
    Subcellular responses to phosphate limited and sucrose replete conditions in plant cells
  • Martynowicz, David - MSC.MCB - December 8, 2015
    (Advisor: M. Coppolino)
    Analysis of Munc18c and Syntaxin4 function during tumour cell invasion
  • Wroblewski, Charles - MSC.MCB - December 7, 2015
    (Advisor: M. Kimber)
    Characterization of the interactions between CcmM and Rubisco – key players in organizing the β-carboxysome interior
  • Kell, Laura - MSC.MCB - December 4, 2015
    (Advisor: A. Clarke)
    Characterization and investigation of novel inhibitory compounds of O-acetyltransferase A (OatA) from Staphylococcus aureus
  • Wyse, Brandon - MSC.MCB - November 27, 2015
    (Advisor: K. Yankulov)
    Epigenetic inheritance in Saccharomyces cerevisiae: the competition between CAF-I and Rrm3p for the DNA sliding clamp PCNA
  • Pasman, Yfke - PHD.MCB - November 17, 2015
    (Advisor: A. Kaushik)
    Bovine antibody genetics, structure and antigenization for disease prevention
  • Lockhart, Morgan - MSC.MCB - October 30, 2015
    (Advisor: S.Rothstein)
    An investigation of the role of stress-responsive aldo-keto reductases in Arabidopsis thaliana
  • Ecclestone, Mark - MSC.MCB - October 8, 2015
    (Advisor: A. Clarke)
    Investigation of protein and inhibitor binding to O-Acetylpeptidoglycan esterase 1 from Neisseria gonorrhoeae
  • Facciuolo, Antonio - PHD.MCB - September 24, 2015
    (Advisor: L. Mutharia)
    Proteomic and immunological investigation of Mycobacterium avium subspecies paratuberculosis secreted proteins
  • Roach, Elyse - PHD.MCB - September 18, 2015
    (Advisor: C. Khursigara)
    Investigation of the structures of ZapA and ZapD from Escherichia coli and their roles in bacterial cell division
  • Deol, Reema - MSC.MCB.TOX - September 4, 2015
    (Advisor: D. Josephy)
    Substrate specificity of human N-acetyltransferase 8 for aromatic cysteine conjugates
  • Jaipargas, Erica Ashley - MSC.MCB - August 18, 2015
    (Advisor: J. Mathur)
    Investigations on mitochondria pleomorphy and interactions with the endoplasmic reticulum and peroxisomes
  • Liu, Yang - PHD.MCB - July 10, 2015
    (Co-Advisors: P. Krell / É. Nagy)
    Functional analysis of the baculovirus AcMNPV me53/ME53
  • Marom, David - MSC.MCB - May 4, 2015
    (Advisor: J. Wood)
    The role of the C-terminal coiled-coil in the cellular localization and in the osmotic stress response of transporter ProP
  • Roufayel, Rabih - PHD.MCB - April 30, 2015
    (Advisor: D. Mosser)
    Regulation of heat-induced apoptosis by the loss of miR-23a-dependent control of NOXA in human cells and its suppression by HSP70 
  • Meeks, Tylar - MSC.MCB - April 29, 2015
    (Advisor: J. Colasanti)
    Investigating the Function of the Arabidopsis thaliana INDETERMINATE DOMAIN2 gene
  • Bertin, David - MSC.MCB - April 29, 2015
    (Advisor: R. Lu)
    Potential new aging model Schmidtea mediterranea undergoes gradual senescence and experiences accelerated senescence at elevated temperature
  • Bolte, Erin - MSC.MCB - April 29, 2015
    (Advisor: E. Allen-Vercoe)
    Characterization of the Human Gut Microbiota Metabolite Profile in Autism Spectrum Disorder
  • Anillo, Maria - MSC.MCB - April 27, 2015
    (Advisor: J. Dawson)
    Hypertrophic cardiomyopathy-linked α-cardiac actin mutations and their role on actomyosin interactions
  • Zhao, Qianru (Ruby) - PHD.MCB - April 24, 2015
    (Advisor: M. Emes)
    Regulation of starch biosynthesis in Arabidopsis thaliana
  • Jenkins, Andrew - MSC.MCB - April 23, 2015
    (Advisor: G. Harauz)
    Conformational transitions of 18.5-kDa myelin basic protein studied by fluorescence spectroscopy and Förster resonance energy transfer
  • Hoang, Tuan - PHD.BIG - April 21, 2015
    (Co-Advisors: M. Jelokhani-Niaraki, WLU and R. Merrill)
    Exploring the structure and function of human uncoupling proteins: A biophysical approach
  • Fletcher, Andrew - MSC.BINF - April 16, 2015
    (Advisor: G. van der Merwe)
    Microarray analysis of DV10 Saccharomyces cerevisiae during second fermentation under oenological conditions
  • Clarke, Matt - MSC.MCB - January 16, 2015
    (Advisor: S. Graether)
    The K2 Dehydrin: an intrinsically disordered membrane protector
  • Rahman, Mohammad Atikur - PHD.MCB - January 9, 2015
    (Advisor: A. Nassuth)
    Role of ice proteins in freezing tolerance and stomatal development in grapes
  • Mishra, Vadika - MSC.MCB - January 8, 2015
    (Advisor: J. Dawson)
    Characterization of short ADP ribosylated oligomers developed by modification in F-actin structure
  • Teresinski, Howard - MSC.MCB - January 7, 2015
    (Advisor: R. Mullen)
    Distinct C-terminal amino acid sequence motifs serve as the targeting signals for outer mitochondrial membrane and plastid outer envelope TA proteins
  • Samson, Jonathan - MSC.MCB - January 6, 2015
    (Advisor: A. Clarke)
    Elucidating the enzymatic function of resuscitation promoting factor B, RpfB, from Mycobacterium tuberculosis

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