amfAR Request for Proposals: Targeted Biomedical Research - LOI Stage

This RFP solicits proposals relevant to exploring the mechanisms for HIV persistence and the potential for HIV eradication. Highly active antiretroviral therapy (HAART) has significantly impacted the health of individuals infected with HIV-1. However, if therapy is interrupted, there is a rapid resumption of viral replication. Understanding the mechanisms by which the virus is able to persist in the face of therapy is necessary in order to identify strategies that may interrupt viral persistence and ultimately lead to viral eradication. amfAR wishes to support basic, pre-clinical, clinical, and especially translational research exploring the mechanisms whereby HIV infection persists; the chronic nature of viral reservoirs and latency; and barriers to the eradication of HIV, with the potential goal of ultimately eliminating HIV infection.

QUALIFICATIONS:  Investigators must hold a doctoral degree and be affiliated with a nonprofit research institution.

LOI FOMS AND INSTRUCTIONS:  Interested applicants will be required to submit a letter of intent (LOI) on amfAR-provided forms.   LOI forms and instructions may be obtained by sending an e-mail to grants@amfar.org.  E-mails should include (1) investigator’s name, doctoral degree(s), and job title(s), (2) name of the applicant institution, and (3) proposed project title.

AVAILABLE FUNDING AND PERFORMANCE PERIOD:  Maximum total costs: $180,000 including indirect costs at a maximum of 20% of direct costs for a one year performance period starting February 1, 2013.

Please click here to access the full RFP.

EXTERNAL LOI DEADLINE:  September 27, 2012 - submitted by e-mail to grants@amfar.org  by 5:00 pm (EDT)