Professor, College of Biological Science, University of Guelph
David Josephy graduated from the University of Toronto and the University of British Columbia and was a post-doctoral fellow at NIEHS, North Carolina. He joined the Department of Chemistry, University of Guelph (Ontario, Canada) in 1983. The biochemistry faculty at Guelph joined the new Department of Molecular and Cellular Biology in 2004. Josephy has taught Biochemistry to thousands of students, at introductory, intermediate, and graduate levels. He developed a senior-level course in Biochemical Toxicology and is the co-author of "Molecular Toxicology, 2nd ed." (Oxford University Press, 2006).
Josephy has supervised more than 20 graduate students and published more than 100 scientific papers. His research interests include the analytical chemistry of environmental carcinogens; mechanisms of xenobiotic bioactivation; and enzyme structure and function. The concept of bacterial mutagenicity strains expressing recombinant human enzymes of bioactivation, pioneered in the Josephy lab., has been widely adopted. Josephy received the Society of Toxicology of Canada Henderson Award (1996) for outstanding contributions to toxicology in Canada. Josephy was co-organizer of the Environmental Mutagen Society Special Conference "Breast Cancer and Environmental Mutagens: Bridging Molecular Research to Medicine and Public Health" (Sept. 2001) and subsequently received an EMS Special Recognition Award. Josephy was Secretary to the Organizing Committee for the International Congress of Toxicology (ICTXI), held in Montreal in July 2007.
Josephy has served on many granting agency review panels in Canada and is a member of the College of Reviewers for the Canada Research Chairs program. He has served as a member of the Council of the Society of Toxicology of Canada and is a member of the editorial boards of the journals Mutation Research and Toxicology.