Academic Course Information

Fall 2011

University of Guelph Introductory Biochemistry — BIOC*2580

Instructors: Dr Enoka Wijekoon
Office: Science Complex
Office hours: 
E-mail: BIOC2580@.uoguelph.ca

Instructor: Dr. David Josephy
Office:Science Complex 2253
Office hours: 
E-mail: BIOC2580@uoguelph.ca



Web site:


Laboratory: Jaspreet Kaur, Coordinator, Science Complex 3115
e-mail BIOC2580 @uoguelph.ca (put "LAB" on the subject line.)
Course synopsis: A broad outline of biochemistry, with emphasis on protein and enzyme structure and function, with a brief introduction to intermediary metabolism.

The unifying theme in this course is the oneness of all earthly life forms, attesting to their common evolutionary origin. As described in the University's Learning Objectives, in addition to studying the factual content of the science, we will also consider its historical development, experimental basis, and relationship to other aspects of science and society.

Topics to be covered:

  • Structure and properties of amino acids
  • Structure and organization of proteins
  • Enzyme mechanisms and kinetics
  • Structure and properties of carbohydrates
  • Structure and properties of nucleosides and nucleic acids
  • Energy relationships in biochemical processes
  • Principles of biochemical reactions
  • Energy metabolism including glycolysis, tricarboxylate cycle, beta-oxidation and amino acid breakdown pathways.
  • Biological membranes and the oxidative phosphorylation process
Method of Presentation:


Lehninger's Principles of Biochemistry
by D.L. Nelson and M.M. Cox, 5th Ed (2008) W.H. Freeman.
Grade Assessment:
Midterm exam30%
Final exam45%
Students must pass the combined examination component, i.e. earn 37.5 out of 75 for the sum of the non laboratory components, in order to pass the course as a whole. This means that a high laboratory mark cannot be used to secure a pass if the examinations are failed. Students must also pass the laboratory component as a unit, i.e. earn 12.5 out of 25. In cases where these standards are not achieved, the final mark assigned will either be the mark calculated or 47%, whichever is less.

College policy precludes changing the marking scheme for individual students, except in case of illness.

Laboratories: All labs are in Science Complex rooms 3110-3112

Note: laboratory sessions begin on Monday Sept 20.

Each student must, in advance:

  • obtain a current laboratory manual (sold by Dept of Microbiology, location TBA).
  • obtain a hardcover 7" × 9" notebook (not spiral bound, not looseleaf) for recording lab results.
  • have a lab coat and approved safety goggles for use in the lab (see sales info). Lab coats may be purchased from the Chemistry Club



University of Guelph