Some characterized genes and pertinent mutants with clear cytoskeleton-linked defects in the morphogenesis of one or more model cell-types
| Gene | Major mutant Phenotype | Gene product | References |
ANGUSTIFOLIA |
Narrow leaves, 2-branched trichomes | C-terminal binding protein / BARS-like | Folkers, 2002Kim, 2002 |
| BRICK1 (maize)putative homolog At2g22640 | Defective lobe formation in leaf epidermal cells, stomatal complex, hairs aberrant | Novel actin interacting protein. Homology to HSPC300 | Frank & Smith, 2002,2003 |
| CROOKED At4g01710 |
Distorted trichomes, unexpanded Epidermal cells, short thickroot-hairs | Smallest subunit ARPC5 (p16 homolog) of the ARP2/3 complex. | Mathur, 2003aLe 2003Li 2003 |
| DEFORMEDROOT HAIRS1At3g18780 | Aberrant root-hair initiation site, aberrant tip-growth | ACTIN2 | Ringli, 2002Nishimura, 2003 |
| DISTORTED1 At1g13180 |
Distorted trichomes, unexpanded Epidermal cells, short thickroot-hairs | Actin related protein 3 (ARP3), large subunit of ARP2/3 complex | Mathur, 2003bLe 2003Li 2003 |
| DISTORTED2 At1g30825 |
Distorted trichomes, unexpanded Epidermal cells, short thickroot-hairs | Fourth largest ARPC2 subunit (p35 homolog) of the ARP2/3 complex | El-Assal, 2004Saedler, 2004 |
| ECTOPIC ROOT HAIRS3, FAT ROOT, BOTERO1, FRAGILE FIBER2, LUE1 At2g34560 |
Ectopic root hairs, swollen root, defective cell wall, stem fragility | Katanin-p60-like, also calledAtKSS | Burk, 2001 Bichet, 2001Webb, 2002Bouquin, 2003 |
| FASS / TONNEAU2 At5g18580 |
Swollen cells, abnormal cortical microtubules, random divisions | Novel higher plant protein, C-terminal similarity to B' regulatory subunits of type 2A protein phosphatases. | Camilleri, 2002 |
| KIESEL At2g30410 |
Weak allele shows swollen trichomes; strong alleles are embryo lethal | Tubulin folding co-factor A | Kirik, 2002aMayer, 2002 |
| LEFTY1/LEFTY2 At1g04820 / At4g14960 |
Shoots, roots twist to the left; right-handed cortical microtubules | a-tubulin 4 (TUA4) / a -tubulin 6 (TUA6) | Thitamadee, 2002Abe, 2004 |
| MICROTUBULE ORGANIZATION1 / GEMINI1 At2g35630 |
Temperature sensitive, dwarf, short, swollen cells, pollen mother cell defects | TOG-XMAP 215 family; homolog to tobacco TMBP200 | Whittington,2001Twell, 2002 |
| PLEIADE At5g51610 |
Branched root hairs, cytokinesis defects | Microtubule associated protein AtMAP65-3 | Muller, 2004 |
| PORCINO At4g39920 |
Weak allele shows swollen trichomes; Strong alleles embryo lethal | Tubulin folding co-factor C | Kirik, 2002bMayer, 2002 |
| PROPYZAMIDE- HYPER-SENSITIVE1 At5g23720 |
Left handed helical growth of roots, increased sensitivity to microtubule depolymerizing drugs | Novel Mitogen-activated protein kinase (MAPK) phosphatase-like | Naoi, 2004 |
| SPIKE1 At4g16340 |
Aberrant leaf, trichome, cotyledon-cell shape | Adapter protein CDM family, putative ROP regulator | Qiu, 2002 |
| SPIRAL1 At2g03680 |
Right-handed helical growth of hypocotyl / root | Novel microtubule-localized protein | Nakajima, 2004 |
| STICHEL At2g02480 |
Un-branched trichomes on leaves | Novel protein with ATP-binding eubacterial DNA-polymerase III gamma-subunit | Ilgenfritz, 2003 |
| WAVE-DAMPENED2 At5g28646 |
Suppressed root-waving, rotational polarity and anisotropic expansion altered | KLEEK domain containing protein, shows similarity to microtubule destabilizing Stathmin proteins | Yuen, 2003 |
| WURM At3g27000 |
Distorted trichomes, unexpanded epidermal cells, short thick root-hairs | Actin related protein (ARP) 2, homolog large subunit of ARP2/3 complex | Mathur, 2003bLe 2003Li 2003 |
| ZWICHEL At5g65930 |
Short, swollen, less branched trichomes | Kinesin-like calmodulin-binding protein (KCBP) | Oppenheimer1997Reddy,1996 |
References
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