TheWood Lab

Publications
(for links to ejournals, see PubMed)

REVIEW ARTICLES AND BOOK CHAPTERS

RESEARCH ARTICLES

DATABASE ENTRIES

UNIVERSITY POLICY REVIEWS

REVIEW ARTICLES AND BOOK CHAPTERS

Romantsov and J.M. Wood (2008) Cardiolipin and the Osmotic Stress Responses of Bacteria.  Biochim. Biophys. Acta.  Submitted.

K. Altendorf, I.R. Booth, J. Gralla, J.-C. Greie, A.Z. Rosenthal and J.M. Wood (2008) EcoSal Web Edition: Module 5.4.5 Osmotic Stress, American Society for Microbiology. Submitted.

J.M. Wood (2007) Bacterial Osmosensing Transporters in Osmosensing and Osmosignaling, D. Häussinger and H. Sies, eds. Meth. Enzymol. 428:77-107.

J.M. Wood (2006) Perspective on Osmosensing by Bacteria.  Science’s STKE 357:pe43.

B. Poolman, J.J. Spitzer, and J.M. Wood. (2004) Bacterial Osmosensing: roles of membrane structure and electrostatics in lipid-protein and protein-protein interactions.  Biochim. Biophys. Acta  1666:88-104.

J.M. Wood, E. Bremer, L.N. Csonka, R. Kraemer, B. Poolman, T. van der Heide and L.T. Smith (2001) Osmosensing and osmoregulatory compatible solute accumulation by bacteria.  Comp. Biochem. Physiol. Part A 130:437-460.

J.M. Wood (1999) Osmosensing by Bacteria: Signals and Membrane-Based Sensors.  Microbiol. Mol. Biol. Rev. 63:230-262.

A. Ward, J. O'Reilly, N.G. Rutherford, S.M. Ferguson, C.K. Hoyle, S.L. Palmer, J.L. Clough, H. Venter, H. Xie, G.J. Litherland, G.E.M. Martin, J. M. Wood, P.E. Roberts, M.A.T. Groves, W.-j. Liang, A. Steel, B.J. McKeown and P.J.F.  Henderson (1999) Expression of prokaryotic membrane transport proteins in Escherichia coli K-12.  Biochem. Soc. Trans. 27:893-899.

J.M. Wood (1997) Osmoadaptation by Bacteria.  The Biochemist 9:22-25.

K.J. Miller & J.M. Wood (1996) Osmoadaptation by Rhizosphere Bacteria. Annu. Rev. Microbiol. 50:101-136.

R.T. Vögele, E.V. Marshall & J.M. Wood (1995) Chapter 2. Membrane Permeability and Transport in Bioenergetics: A Practical Approach. G.C. Brown and C.E. Cooper, ed. Oxford University Press.

J.M. Wood (1988) Proline Porters Effect the Utilization of Proline as Nutrient or Osmoprotectant for Bacteria. J. Membrane Biol. 106:183-202.

J.L. Milner, B. Vink & J.M. Wood (1987) Transmembrane Amino Acid Flux in Bacterial Cells. CRC Critical Reviews in Biotechnology. 5:1-47.

RESEARCH ARTICLES

D.E. Culham, Y.I. Vernikovska, N. Tschowri , R.A.B. Keates, J.M. Wood and J.M. Boggs (2008) Periplasmic loops of osmosensory transporter ProP in Escherichia coli are sensitive to osmolality.  Biochem., In Press October 2008. (Collaboration with Ya.I. Vernikovska and J.M. Boggs (Hospital for Sick Children and University of Toronto), R.A.B. Keates (University of Guelph))

T. Romantsov, L. Stalker, D.E. Culham and J.M. Wood (2008) Cardiolipin controls the osmotic stress response and the subcellular location of transporter ProP in Escherichia coli.  J.Biol.Chem. 283:12314-12323.

Y. Tsatskis , S.C. Kwok, E. Becker, C. Gill, M.N. Smith, R.A.B. Keates, R.S. Hodges and J.M. Wood (2008) Core residue replacements cause coiled-coil orientation switching in vitro and in vivo: structure-function correlations for osmosensory transporter ProP. Biochem. 47:60-72. (Collaboration with S. Kwok and R.S. Hodges (University of Colorado Denver), R.A.B. Keates (University of Guelph))

T. Romantsov, D.E. Culham and J.M. Wood (2008) Roles of K⁺, H⁺, H₂O and the membrane potential in solute transport mediated by Major Facilitator Superfamily members ProP and LacY.  Biochem. 47:8176-8185.

M. Smith , S.C. Kwok, R.S. Hodges and J.M. Wood (2007)  Structural and Functional Analysis of ProQ: An Osmoregulatory Protein of Escherichia coli. Biochem. 46:3084-3095.  (Collaboration with S. Kwok and R.S. Hodges (University of Colorado Denver))

F. Liu, D.E. Culham, Ya.I. Vernikovska, R.A.B. Keates, J.M. Boggs and J.M. Wood (2007. Structure and Function of the XII^th Transmembrane Segment in Osmosensor and Osmoprotectant Transporter ProP of Escherichia coli.  Biochem.  46:5647-5655. (Collaboration with F. Liu, Ya.I. Vernikovska and J.M. Boggs (Hospital for Sick Children and University of Toronto), R.A.B. Keates (University of Guelph))

T. Romantsov, S. Helbig , D.E. Culham, C. Gill, L. Stalker and J.M. Wood (2007) Cardiolipin promotes polar localization of osmosensory transporter ProP in Escherichia coli.  Mol Microbiol. 64:1455-1465.

A. Hillar, D.E. Culham, Ya.I. Vernikovska, J.M. Wood and J.M. Boggs (2005) Formation of an antiparallel, intermolecular coiled-coil is associated with in vivo dimerization of osmosensor and osmoprotectant transporter ProP in Escherichia coli.  Biochem.  44:10170-10180. (Collaboration with A. Hillar, Ya.I. Vernikovska and J.M. Boggs (Hospital for Sick Children and University of Toronto))

Y. Tsatskis, J. Khambati, M. Dobson, M. Bogdanov, W. Dowhan and J.M. Wood (2005) The osmotic activation of transporter ProP is tuned by both its C-terminal coiled-coil and osmotically induced changes in phospholipid composition.  J. Biol. Chem. 280:41387-41394. (Collaboration with M. Bogdanov and W. Dowhan (University of Texas Houston))

J.M. Wood, D.E. Culham, A. Hillar, Ya.I. Vernikovska, F. Liu, J.M. Boggs, & R.A.B. Keates. (2005) A structural model for the osmosensor, transporter and osmoregulator ProP of Escherichia coli.  Biochem.  44:5634-5646. (Collaboration with A. Hillar, Ya.I. Vernikovska, F. Liu and J.M. Boggs (Hospital for Sick Children and University of Toronto))

M. Smith, R.A. Crane, R.A.B. Keates & J.M. Wood.  (2004)  Overexpression, purification and characterization of ProQ, a post-translational regulator for osmoregulatory transporter ProP of Escherichia coli.  Biochem. 43:12979-12989. (Collaboration with R.A.B. Keates (University of Guelph))

A. Ly, J. Henderson, A. Lu, D.E. Culham & J.M. Wood.  (2004)  The osmoregulatory systems of Escherichia coli:  Identification of BCCT Family Member BetU and distributions of betU and trkG among pathogenic and non-pathogenic isolates.  J Bacteriol. 186: 296-306. 

A. Hillar, B. Tripet, D. Zoetewey, J.M. Wood, R.S. Hodges & J.M. Boggs.  (2003)  Detection of Alpha-Helical Coiled-Coil Dimer Formation by Spin-labeled Synthetic Peptides:  A Model Parallel Coiled-Coil Peptide and the Antiparallel Coiled-Coil Formed by a Replica of the ProP C-terminus.  Biochem.  42:15170-15178. (Collaboration with A. Hillar, Ya.I. Vernikovska and J.M. Boggs (Hospital for Sick Children and University of Toronto), B. Tripet, D. Zoetewey and R.S. Hodges (University of Colorado Denver))

D.L. Zoetewey, B.P. Tripet, T.G. Kutateladze, M.J. Overduin, J.M. Wood & R.S. Hodges.  (2003)  Solution Structure of the Cytoplasmic Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.  J. Mol. Biol. 334:1063-1076 .  (Collaboration with D. Zoetewey, B. Tripet, T.G. Kutateladze, M.J. Overduin and R.S. Hodges (University of Colorado Denver))

R.D. Sleator, J.M. Wood & C. Hill.  (2003)  Transcriptional Regulation and Post-Translational Activity of the Betaine Transporter BetL in Listeria monocytogenes is Controlled by Environmental Salinity.  J Bacteriol. 185: 7140-7144.

D.E. Culham, A. Hillar, J. Henderson, A. Ly., Ya.I. Vernikovska, K.I. Racher, J.M. Boggs & J.M. Wood.  (2003)  Creation of a Fully Functional Cysteine-less Variant of Osmosensor and Proton-Osmoprotectant Symporter ProP from Escherichia coli and its Application to Assess the Transporters Membrane Orientation.  Biochem.  42:11815-11823. (Collaboration with A. Hillar, Ya.I. Vernikovska and J.M. Boggs (Hospital for Sick Children and University of Toronto))

D.E. Culham, J. Henderson, R.A. Crane & J.M. Wood.  (2003)  Osmosensor ProP of Escherichia coli responds to the concentration, chemistry and molecular size of osmolytes in the proteoliposome lumen.  Biochem. 42:410-420.     

D.E. Culham, A. Lu, M. Jishage, K.A. Krogfelt, A. Ishihama & J.M. Wood (2001) The osmotic stress response and virulence in pyelonephritis isolates of Escherichia coli:  contributions of RpoS, ProP, ProU and other systems. Microbiology147:1657-1670.  (Collaboration with K.A. Krogfelt (Statens Serum Institut , Denmark ); A. Ishihama and M. Jishage (National Institute of Genetics , Japan ))

K.I. Racher, D.E. Culham & J.M. Wood (2001) Requirements for osmosensing and osmotic activation of transporter ProP from Escherichia coli.  Biochem. 40:7324-7333.

D.E. Culham & J.M. Wood (2000) An Escherichia coli Reference Collection Group B2- and uropathogen-associated polymorphism in the rpoS-mutS region of the Escherichia coli chromosome. J. Bacteriol. 182:6272-6276.

G.F. White, K.I. Racher, A. Lipski, F.R. Hallett & J.M. Wood. (2000) Physical properties of liposomes and proteoliposomes prepared from Escherichia coli polar lipids.  Biochim. Biophys. Acta 1468:175-186.  (Collaboration with F.R. Hallett & G.F. White ( Guelph ); A. Lipski ( University of Osnabrueck , Germany ))

D.E. Culham, B. Tripet, K.I. Racher, R.T. Voegele, R.S. Hodges & J.M. Wood.  (2000) Role of the carboxyl terminal a-helical coiled-coil domain in osmosensing by transporter ProP of Escherichia coli. J. Molecular Recognition 13:1-14. (Collaboration with R.S. Hodges & B. Tripet ( University of Alberta ))

S.V. MacMillan, D.A. Alexander, D.E. Culham, H.J. Kunte, E.V. Marshall, D. Rochon & J.M. Wood. (1999) The ion coupling and organic substrate specificities of osmoregulatory transporter ProP in Escherichia coli. Biochim. Biophys. Acta.  1420:30-44. (Collaboration with H.J. Kunte ( University of Bonn , Germany ))

H.J. Kunte, D.E. Culham, R. Crane, D. Richmond & J.M. Wood. (1999) Protein ProQ and osmotic activation of compatible solute transporter ProP of Escherichia coli.  J. Bacteriol.181:1537-1543.

K. Racher, R.T. Vögele, E.V. Marshall, D.E. Culham, J.M. Wood, H. Jung, M. Bacon, M.T. Cairns, S.M. Ferguson, W.-J. Liang, P.J.F. Henderson, G. White & F.R. Hallett (1999) Purification and reconstitution of an osmosensor:  Transporter ProP of Escherichia coli senses and responds to osmotic shifts. Biochemistry 38:1676-1684. (Collaboration with H. Jung ( University of Osnabrueck , Germany ); P.J.F. Henderson & others (Leeds University, UK ) and F.R. Hallett & G.F. White ( Guelph ))

D.E. Culham, C. Dalgado, C.L. Gyles, D. Mamelak, S. MacLellan & J.M. Wood. (1998) Osmoregulatory transporter ProP influences colonization of the urinary tract by Escherichia coli. Microbiology144:91-102. (Collaboration with C.L. Gyles ( Guelph ))

C. Bayliss, E. Bent, D.E. Culham, S. MacLellan, A.J. Clarke, G.R. Brown & J.M. Wood. (1997) Bacterial genetic loci implicated in the Pseudomonas putida GR12-2R3/canola mutualism: identification of an exudate-inducible sugar transporter. Can. J. Microbiol. 43:809-818. (Collaboration with A.J. Clarke ( Guelph ); G.R. Brown (Agrium, Saskatoon ))

G. White, J. Pencer, B.G. Nickel, J.M. Wood & F.R. Hallett (1996) Optical changes in unilamellar vesicles experiencing osmotic stress. Biophys. J. 71:2701-2715. (Collaboration with F.R. Hallett & G. White ( Guelph ))

M. Ling, S.W. Allen & J.M. Wood. (1994) Sequence analysis identifies the proline dehydrogenase and d¹-pyrroline-5-carboxylate dehydrogenase domains of the multifunctional Escherichia coli PutA protein. J. Mol. Biol. 243:950-956.

D.E. Culham, K.S. Emmerson, B. Lasby, D. Mamelak, B.A. Steer, C.L. Gyles, M. Villarejo & J.M. Wood (1994) Genes encoding osmoregulatory proline/betaine transporters and the proline catabolic enzymes are present and expressed in diverse clinical Escherichia coli isolates. Can. J. Microbiol. 40:397-402. (Collaboration with C.L. Gyles ( Guelph ) and M. Villarejo ( University of California , Davis )

C. Bayliss, B. Lasby, J.M. Wood, G.R. Brown & R. Lifshitz (1993) Mutant derivatives of Pseudomonas putida GR12-2R3 defective in nutrient utilization or cell surface structures show reduced ability to promote canola root elongation. Can. J. Microbiol. 39:1111-1119. (Collaboration with G.R. Brown & R. Lifshitz (Allelix, Inc. and ESSO Ag Biologicals))

E.D. Brown & J.M. Wood (1993) Conformational change and membrane association of the PutA protein are coincident with reduction of its FAD cofactor by proline. J. Biol. Chem. 268:8972-8979.

A. Ertel, A.G. Marangoni, J. Marsh. F.R. Hallett & J.M. Wood (1993) Mechanical properties of vesicles: I. Coordinated analysis of osmotic swelling and lysis. Biophys. J. 64:426-434. (Collaboration with F.R. Hallett & J. Marsh ( Guelph ))

F.R. Hallett, J. Marsh, B.G. Nickel & J.M. Wood (1993) Mechanical properties of vesicles: II. A model for osmotic swelling and lysis. Biophys. J. 64:435-442. (Collaboration with F.R. Hallett, J. Marsh & B.G. Nickel ( Guelph ))

D.E. Culham, B. Lasby, A.G. Marangoni, J.L. Milner, B.A. Steer, R.W. van Nues & J.M. Wood (1992) Isolation and sequencing of Escherichia coli gene proP reveals unusual structural features of the osmoregulatory proline/betaine transporter, ProP. J. Mol. Biol. 229:268-276.

E.D. Brown & J.M. Wood (1992) Redesigned purification yields a fully functional PutA protein dimer from Escherichia coli. J. Biol. Chem. 267:13086-13092.

J.L. Milner & J.M. Wood (1989) Insertion proQ220::Tn5 alters regulation of proline porter II, a transporter of proline and glycine betaine in Escherichia coli. J. Bacteriol. 171:947-951.

J.L. Milner, S. Grothe & J.M. Wood (1988) Proline porter II is activated by a hyperosmotic shift in both whole cells and membrane vesicles of Escherichia coli K12. J. Biol. Chem. 263:14900-14905.

J.M. Wood, K.A.C.C. Taylor, D.J. McClellan, G.G. Lawrie, R.L. Krogsrud & T.J. Beveridge (1987) Isolation and characterization of monoclonal antibodies to proline dehydrogenase from Escherichia coli K-12. J. Biochem. Cell Biol. 65:507-513. (Collaboration with T.J. Beveridge ( Guelph ))

J.L. Milner, D.J. McClellan & J.M. Wood (1987) Factors reducing and promoting the effectiveness of proline as an osmoprotectant in Escherichia coli K-12. J. Gen. Microbiol. 133:1851-1860.

J.M. Wood (1987) Membrane association of proline dehydrogenase in Escherichia coli is redox dependent. Proc. Natl. Acad. Sci., U.S.A. 84:373-377.

A. Crawford, B.K. Hunter & J.M. Wood (1987) NMR spectroscopy reveals the metabolic origins of proline excreted by an Escherichia coli derivative during growth on [13C] acetate. Appl. Environ. Microbiol.53:2445-2451.  (Collaboration with A. Crawford & B.K. Hunter ( Queens University ))

J.M. Wood, J.G. Wise, A.E. Senior, M. Futai & P.D. Boyer (1987) Catalytic properties of the F₁-ATPase from Escherichia coli K-12 and its genetic variants as revealed by ¹⁸O-exchanges. J. Biol. Chem. 262:2180-2186. (Research conducted during sabbatical leave in the laboratory of P.D. Boyer ( University of California , Los Angeles ); Collaboration with M. Futai ( Okayama , Japan ); A.E. Senior & J.G. Wise ( Rochester , NY ))

S. Grothe, R.L. Krogsrud, D.J. McClellan, J.L. Milner & J.M. Wood (1986) Proline Transport and Osmotic Stress Response in Escherichia coli K-12. J. Bacteriol. 166:253-259.

C.-C. Chen, T. Tsuchiya, Y. Yamane, J.M. Wood & T.H. Wilson (l985) Na⁺ (Li⁺) - Proline Cotransport in Escherichia coli. J. Membrane Biol. 84:l57-l64. (Collaboration with T.H. Wilson and others ( Harvard University , Boston , MA ))

S.B. Graham, J.T. Stephenson & J.M. Wood (l984) Proline Dehydrogenase from Escherichia coli Kl2: Reconstitution of a functional membrane association. J. Biol. Chem. 259:2656-266l.

D.E. Rancourt, J.T. Stephenson, G.A. Vickell & J.M. Wood (l984) Proline excretion by Escherichia coli Kl2. Biotech. Bioeng. 26:74-80.

M.E. Stalmach, S. Grothe & J.M. Wood (l983) Two proline porters in Escherichia coli Kl2. J. Bacteriol. 156:48l-486.

J.L.A. Abrahamson, L.G. Baker, J.T. Stephenson & J.M. Wood (l983) Proline Dehydrogenase from Escherichia coli Kl2: Properties of the membrane associated enzyme. Europ. J. Biochem. 134:77-82.

T.M. Finan, J.M. Wood & D.C. Jordan (l983) Symbiotic properties of C4-dicarboxylic acid transport mutants of Rhizobium leguminosarum. J. Bacteriol. 154:l403-l4l3.  (Collaboration with T.M. Finan & D.C. Jordan ( Guelph ))

J.M. Wood (l982) The membrane enzyme complex required for L-proline transport and utilization in Escherichia coli Kl2. Biophys. J. 37:19-20.

M. Clancy, K.A. Madill & J.M. Wood (l98l) The biochemical and genetic requirements for L-proline chemotaxis in Escherichia coli Kl2. J. Bacteriol. 146:902-906.

J.M. Wood (l98l) The genetics of L-proline utilization in Escherichia coli Kl2. J. Bacteriol. 146:895-90l.

T.M. Finan. J.M. Wood & D.C. Jordan (l98l) Succinate transport in Rhizobium leguminosarum. J. Bacteriol. 148:l93-202.  (Collaboration with T.M. Finan & D.C. Jordan ( Guelph ))

J.M. Wood & D. Zadworny (l980) Amplification of the put genes and identification of the put gene products in Escherichia coli Kl2. Can. J. Biochem. 58:787-796.

R.R. Anderson, R. Menzel & J.M. Wood (l980) Biochemistry and regulation of a second L-proline transport system in Salmonella typhimurium. J. Bacteriol. 141:l07l-l076. (Collaboration with J. Roth & R. Menzel ( University of Utah , Salt Lake City ))

J.M. Wood, D. Zadworny, E. Lohmeier & J.H. Weiner (l979) Hybrid plasmids complement a putP mutation in Escherichia coli Kl2. Can. J. Biochem. 57:l328-l330.  (Collaboration with J.H. Weiner & E. Lohmeier ( University of Alberta ))

J.M. Wood & D. Zadworny (l979) Characterization of an inducible porter required for L-proline catabolism by Escherichia coli Kl2. Can. J. Biochem. 57:1191-1199.

G.D. Sprott, J.M. Wood, W.G. Martin & H. Schneider (l977) A relation between amino acid hydrophobicity and rate of uptake in Escherichia coli Kl2. Biochem. Biophys. Res. Commun. 76:l099-1106.  (Conducted in the laboratory of H. Schneider ( Ottawa , ON ))

P.A. Janick, G.B. Grunwald & J.M. Wood (l977) The effects of N-ethylmaleimide on active amino acid transport in Escherichia coli. Biochim. Biophys. Acta 464:328-337.  (Conducted in the laboratory of L.A. Heppel ( Ithaca , NY ))

J.M. Wood (l975) L-leucine transport in Escherichia coli:  The resolution of multiple transport systems and their coupling to metabolic energy. J. Biol. Chem. 250:4477-4485.  (Conducted in the laboratory of L.A. Heppel ( Ithaca , NY ))

DATABASE ENTRIES

J.M. Wood, D.E. Culham, A. Hillar, Ya.I. Vernikovska, F. Liu, J.M. Boggs, & R.A.B. Keates (Dec., 2004) Theoretical model of the Proton-Proline Symporter ProP.  Protein Databank (PDB), PDB ID 1Y8S and RCSB ID RCSB031259.

A. Ly & J.M. Wood.  July, 2002.  Escherichia coli clinical isolate HU734, BetU complete cds.  NCBI, Genbank Sequence Submission, Acc. #AF532988.

D.E. Culham & J.M. Wood.  June, 2000.  Escherichia coli HU734 lipoprotein NlpD (nlpD); sigma factor RpoS (rpoS) and unknown gene 1.  National Center for Biotechnology Information (NCBI), Genbank Sequence Submission, Accession # AF275947.

D.E. Culham & J.M. Wood.  May, 2000.  Escherichia coli CFT073 lipoprotein NlpD (nlpD); sigma factor RpoS (rpoS) b2740 gene and unknown genes.  National Center for Biotechnology Information (NCBI), Genbank Sequence Submission, Accession #AF270497.

D.E. Culham & J.M. Wood.  October, 1996.  Escherichia coli HU734 compatible solute transporter ProP (proP).  National Center for Biotechnology Information (NCBI), Genbank Sequence Submission, Accession #U75904.

D.E. Culham & J.M. Wood.  October, 1995.  Escherichia coli K-12 ProQ (proQ) and Prc (prc).  National Center for Biotechnology Information (NCBI), Genbank Sequence Submission, Accession #L48409.

M. Ling & J.M. Wood.  January, 1994.  Escherichia coli K12 proline dehydrogenase and delta-1-pyrroline-5- carboxylate dehydrogenase (putA).  National Center for Biotechnology Information (NCBI), Genbank Sequence Submission, Accession #U05212.

D.E. Culham & J.M. Wood.  1993.  Escherichia coli K-12 proline/betaine transporter (proP) National Center for Biotechnology Information (NCBI), Genbank Sequence Submission, Accession #M83089.

UNIVERSITY POLICY REVIEWS

Presidential Task Force on Accessibility (2004) Final Report

Employment and Educational Equity Office, University of Guelph (1994) Report on the Graduate Student Educational Equity Survey

Employment and Educational Equity Office, University of Guelph (1993) Phase I Report on the Graduate Student Educational Equity Study

Employment and Educational Equity Office, University of Guelph (1991) Employment Equity Assessment

Updated November 2008