We study the neurobiological basis of various cognitive functions in rodent models. Current work in the lab includes analysis of:
1. The roles of various neurotransmitter systems and downstream mechanisms in memory storage, destabilization, and modification.
2. The involvement of GABA-mediated inhibition in efficiency of cognitive processing.
3. Effects of early life enrichment on cognitive performance in normal and transgenic Alzheimer's disease model mice.
4. Epigenetic mechanisms of memory in normal rats and mice, as well as transgenic Alzheimer's disease mice.