Peter Krell (171 Chemistry and Microbiology, Ext. 3368)
Lucy Mutharia (174 Chemistry and Microbiology, Ext. 6349)
Carol V. Schlaht (117 Chemistry and Microbiology, Ext. 3815)
Terry J. Beveridge
Associated Graduate Faculty
BSc, MSc Toronto, PhD Western Ontario - Professor
Anthony J. Clarke
MSc, PhD Waterloo - Professor
BSc British Columbia, MSc, PhD Queen's - Professor
Cecil W. Forsberg
BSA, MSc Saskatchewan, PhD McGill - Professor
Peter J. Krell
BSc, MSc Carleton, PhD Dalhousie - Professor
Joseph S.L. Lam
BSc, PhD Calgary - Professor
Reggie Y.C. Lo
BSc, PhD Alberta - Professor
Lucy M. Mutharia
BSc, MSc Nairobi, PhD British Columbia - Associate Professor
Stephen Y.K. Seah
BSc, MSc National University of Singapore, PhD Sheffield - Assistant Professor
Rosalynn M.W. Stevenson
BSc, PhD Manitoba - Associate Professor
BSc Newcastle, PhD Edinburgh - Professor
Janet M. Wood
BSc Victoria, PhD Edinburgh - Professor
Special Graduate Faculty
BSc Queen's University of Belfast, MSc Queen's, PhD Queen's - Great Lakes Forestry Centre
BSc Manitoba, PhD Queen's - Western Ontario
MD University of Buenos Aires - Western Ontario
BSc, MSc Mysore, PhD Indian Inst. of Science - Waterloo
Eric D. Brown
BSc, MSc PhD Guelph - Assistant Professor
BSc Western Ontario, MSc Toronto, Phd Guelph
The Department of Microbiology offers opportunities for graduate studies leading to the MSc and PhD degrees.
Faculty strengths and academic resources provide for four major fields of study:
1. Physiology and Structure.
- Synthesis, assembly, and function of cell envelope components
(Beveridge, Clarke, Lam, Forsberg, Mutharia,Whitfield).
- Molecular basis for antigenic diversity (Lam, Whitfield).
- Microbial ultrastructure (Beveridge).
- Microbial membrane function (Wood).
- Molecular biology of viruses and viral replication (Dobos, Krell).
4. Microbial Biotechnology.
- Molecular mechanisms in bacterial pathogenesis
(Lam, Lo, Mutharia, Whitfield, Wood).
- Microbial pathogenesis of fish (Dobos, Stevenson).
The department houses the NSERC/Guelph Regional STEM Facility, and is a unit of the Canadian Bacterial Disease
Network of Centres of Excellence.
- Development of anti-microbial agents (Beveridge, Clarke, Whitfield).
- Metal interactions with cell walls; mineral development (Beveridge).
- Pathogenic mechanisms in bacterial disease; antigen diversity; vaccine development
(Lam, Lo, Mutharia,
Stevenson, Whitfield, Wood).
- Microbial enzyme technology (Clarke, Forsberg).
- Vaccine development (Beveridge, Krell, Lam, Lo, Mutharia, Stevenson, Whitfield).
The minimum requirement for admission to the MSc program is a baccalaureate in an honours science program, or the
equivalent, from a recognized university or college. The applicant should have achieved an average standing of at least
second class honours ('B' or 73%) during the last two undergraduate years.
Admission to the program is not restricted to those holding an honours baccalaureate degree in microbiology.
Students must complete at least the minimum university course credit requirements including the departmental seminar
The MSc thesis research project is intended to give the student training and experience in:
- a comprehensive library search on a specific topic related to the research;
- research techniques;
- the design of experiments in collaboration with the research adviser;
- the interpretation of data, and
- writing for scientific publication.
The thesis research should involve experimentation not previously reported in the literature and should lead to a
complete study. Whenever possible, the results should yield publishable data, but this is not an absolute requirement for
the completion of an MSc program.
In the case of a student considering transfer from the MSc program to the PhD program, it is important that the
research project be one which can be expanded in scope and challenge if the transfer is approved.
Admission to the PhD program normally requires at least honours ('B' or a 73% average), in a recognized
baccalaureate program as well as a recognized MSc degree. Transfer from the MSc program to the PhD program will be
considered for a student who has achieved excellent standing at the honours baccalaureate level, and who has
demonstrated a superior performance and particular aptitude for research during the first three semesters of the MSc
program. In exceptional cases, students with an 'A-', (or a minimum average of 80%) standing in a baccalaureate
program and a demonstrated aptitude for research may be granted direct entry into the PhD program.
Course requirements are specified by the student's advisory committee and include the seminars.
The qualifying examination should be completed no later than the end of the third semester for students entering after
completing the MSc degrees and the fifth semester for students entering directly after completing a baccalaureate degree.
For students transferring from the MSc to the PhD degree, the examination will be completed before the end of the
semester following that in which the transfer was approved.
The PhD research project is intended to give the student further, more intensive experience than that of an MSc
program. In addition, the student must develop the ability to generate innovative research ideas and implement them
through carefully designed experiments. The student is expected to develop and demonstrate a high degree of scholarship
and expertise in the chosen specialty, and to exert critical judgement. The research must also yield results which, in the
opinion of the examination committee, warrant publication in reputable scientific journals appropriate to the area of
MSc (Aquaculture) Interdepartmental Program
The Department of Microbiology participates in the master of science in aquaculture program. Professor Stevenson is a
member of the Aquaculture Interdepartmental Group. Her research and teaching expertise includes aspects of
aquaculture; she may serve as adviser for MSc (Aquaculture) students. Please consult the Aquaculture listing for a
detailed description of the MSc (Aquaculture) interdepartmental program.
Biophysics MSc/PhD Program
The Department of Microbiology participates in the MSc/PhD programs in biophysics. Professors Beveridge, Whitfield
and Wood are members of the Biophysics Interdepartmental Group. These faculty members' research and teaching
expertise includes aspects of biophysics; they may serve as advisers for MSc and PhD students in biophysics. Please
consult the Biophysics listing for a detailed description of the graduate programs offered by the Biophysics
| Course/(Credit Value)
|Physiology, Structure and Genetics
Advanced Microbial Physiology (0.5)
|| A study of molecular structure-function relationships fundamental to the survival and growth of bacteria. Topics for
study will be selected from the literature on bacterial cytology, bioenergetics, metabolism, enzymology and
Bacterial Structures and Virulence (0.5)
||A study of the roles of bacterial surface structures (LPS, capsules, flagella, fimbriae, outer membrane proteins) in
the virulence of bacteria. (Jointly offered by the Departments of Microbiology and Pathobiology.)
Microbial Genetics (0.5)
|| A study of recent research developments on the mechanisms of regulation of gene expression, DNA metabolism
and genome analysis of microorganisms. (Offered in even- numbered years.)
Molecular Biology of Viruses (0.5)
||Replication strategies of virus genomes including prototypes of different animal, plant and (some) bacterial virus
families; mechanism and control of viral gene expression; tumor virology; genetically engineered virus vaccines.
Microbial Genetics (0.5)
Bacterial Structures and Virulence (0.5)
| F||(see above)
Advances in Immunology and Immunochemical Techniques (0.5)
||Concepts and current knowledge of the diversity of immune response, experimental systems used in studying immunology, antigen-antibody reaction methods, monoclonal antibodies, antibody engineering, hypersensitivity reactions, autoimmunity, adhesion molecules and homing of cells of the immune system.
Monoclonal Antibodies and Antibody Engineering (0.5)
||A lecture and laboratory course. The theory and process of producing monoclonal antibodies by plasmacytoma
cell fusion and the theories of contemporary technology in engineering antibodies in vitro.
Selected Topics in Microbiology (0.5)
||This course, offered on an irregular basis, provides opportunities for graduate students to study special topics of
mutual interest under the guidance of graduate faculty members with pertinent expertise. Proposed course
descriptions are considered by the Department of Microbiology on an ad hoc basis.
Introductory Seminar (0.25)
| S, F, W
|| A literature review of a selected area of microbiological research concluding with a written research proposal, and
a seminar on the information which is presented within the first two semesters of the program. The course is
required for MSc students, but is optional for PhD students who have taken an equivalent course.
Advanced Seminar (0.25)
| F, W
||Public seminars on current microbiological or allied research topics. MSc students give one seminar while Ph.D.
students give two seminars. The topics must be on subjects other than the student's area of research.
The Office of Graduate Studies has attempted to ensure the accuracy of this
on-line Graduate Calendar. However, the publication of information in this document does not
bind the university to the provision of courses, programs, schedules of studies, fees, or facilities as
listed herein. Other limitations apply.