XII. Course Descriptions

Molecular Biology and Genetics

Department of Animal Biosciences

Department of Molecular and Cellular Biology

Department of Plant Agriculture

Department of Integrative Biology

MBG*1000 Genetics and Society W (3-1) [0.50]
This course covers the basic principles of genetics at work in human society. The roles of genes and inheritance in the biology of humans and the organisms with which we interact. Introduction to some of the social and ethical consequences of genetic knowledge and practice. This is a science course designed primarily for students in the Arts or Social and Applied Human Sciences.
Restriction(s): Students in the BAS, BSC and BSC(ENV) program cannot take this course for credit.
Department(s): Department of Molecular and Cellular Biology
MBG*2040 Foundations in Molecular Biology and Genetics F,W (4-0) [0.50]
This course will develop an understanding of the fundamental concepts in genetics, including patterns of inheritance, allelic variation, gene interaction, linkage, gene mapping and changes in chromosome structure and number. This will be followed by in-depth discussions on gene structure, replication, transcription, translation, recombination, mutation and DNA repair, and an introduction to gene regulation.
Prerequisite(s): 4.00 credits including BIOL*1090
Department(s): Department of Molecular and Cellular Biology
MBG*2400 Fundamentals of Plant and Animal Genetics F (3-2) [0.50]
Fundamental aspects of plant and animal genetics are covered in this course including the chromosomal basis of inheritance, natural and artificial selection, domestication, epigenetics and quantitative traits. Population dynamics and the effect of selection on allele frequencies will be introduced with examples from agricultural crop and animal species and companion animal species. Genomics will be introduced with an emphasis on the development and use of molecular genetic markers in marker assisted selection.
Prerequisite(s): (BIOL*1050 or BIOL*1070), BIOL*1090
Department(s): Department of Animal Biosciences
MBG*3040 Molecular Biology of the Gene F (3-0) [0.50]
In this course, the structure, expression, control and modification of eukaryotic genes will be discussed with an emphasis on the underlying mechanisms and structure/function relationships. Many topics covered in introductory courses are included but discussed at a more advanced level. Students will have the opportunity to learn current genetic concepts and principles through lectures, as well as the application of this knowledge in the real world through primary literature reading and group research projects.
Prerequisite(s): MCB*2050
Department(s): Department of Molecular and Cellular Biology
MBG*3050 Human Genetics W (3-3) [0.50]
This course is designed to introduce the student to the study of biological inheritance in humans. The course includes discussion of the genetic basis of human individual differences, gene frequencies in human populations, human behavioral genetics, human cytogenetics, biochemical genetics and developmental genetics, medical genetics and other aspects of human heredity.
Prerequisite(s): MCB*2050
Department(s): Department of Molecular and Cellular Biology
MBG*3060 Quantitative Genetics W (3-0) [0.50]
This course examines the nature of Mendelian inheritance when extended to quantitative traits that are jointly influenced by the environment and the simultaneous segregation of many genes. Prediction of response to natural and artificial selection in populations will also be studied.
Offering(s): Also offered through Distance Education format.
Prerequisite(s): MBG*2400, 0.50 credits in statistics
Department(s): Department of Animal Biosciences
MBG*3080 Bacterial Genetics F (3-0) [0.50]
This course focuses on the genetics of prokaryotic microorganisms and their viruses. Some major topics covered are: regulation of gene expression, analysis of bacterial and phage genomes, plasmids, transposable elements, and mutation studies.
Prerequisite(s): MBG*2040, MICR*2420
Department(s): Department of Molecular and Cellular Biology
MBG*3100 Plant Genetics W (3-2) [0.50]
This course examines reproduction in plants, genome organization, organelle and polyploid genetics, and analyses of mutations, genetic variation and linkage with classical and modern approaches.
Prerequisite(s): (MBG*2040 or MBG*2400 ), STAT*2040
Department(s): Department of Plant Agriculture
MBG*3350 Laboratory Methods in Molecular Biology S,F,W (1.5-8) [0.75]
This course involves laboratory based instruction in the basic methodologies of Molecular Biology. Students will have the opportunity to develop technical skills and practical knowledge sufficient to perform basic procedures independently, and to diagnose and analyze experimental results obtained with these techniques.
Prerequisite(s): BIOC*2580, MCB*2050
Restriction(s): Registration in BSC.BIOC (major or minor), BIOC:C , BTOX, BTOX:C, BPCH, BPCH:C, MICR(major or minor), MICR:C , MBG (major or minor), PBTC, PLSC (major or minor), TOX, TOX:C
Department(s): Department of Molecular and Cellular Biology
MBG*3660 Genomics W (3-0) [0.50]
This course examines the genomes of eukaryotes and prokaryotes including how genomes are mapped and sequenced, the function of the genome and ethical issues arising from genomic information. How genomic data is used for understanding and treating human disease and for the study of evolution will also be discussed.
Prerequisite(s): MCB*2050
Department(s): Department of Molecular and Cellular Biology
MBG*4020 Genetics of Companion Animals F (3-0) [0.50]
This course explores theoretical and applied aspects of breeding programs for performance, pleasure and hobby animal populations to enhance genetic selection and population viability. Case studies are used to explore the theory and practice of designing practical and sustainable breeding programs that integrate molecular genetics, animal breeding and statistical genomics for a variety of single and multiple birth species.
Prerequisite(s): MBG*3060
Equate(s): ANSC*4020
Department(s): Department of Animal Biosciences
MBG*4030 Animal Breeding Methods and Applications W (3-2) [0.50]
Theoretical and scientific aspects of practical animal breeding programs which lead to genetic improvement of efficiency and profitability of animal production will be presented along with applications to livestock and poultry species. This course integrates quantitative genetics with concepts of statistics, economics, biology and biotechnology and expands into development of practical breeding plans.
Prerequisite(s): MBG*3060
Department(s): Department of Animal Biosciences
MBG*4040 Genetics and Molecular Biology of Development F (3-2) [0.50]
This course provides an examination of the genetic mechanisms that underlie organismal development. The molecular biology of cell determination and differentiation and the genetic control of morphogenesis and pattern formation will be emphasized.
Prerequisite(s): MBG*3040
Department(s): Department of Molecular and Cellular Biology
MBG*4110 Epigenetics F (3-0) [0.50]
This course presents classical non-Mendelian phenomena, including analysis of chromosome breakage, transposition, imprinting and paramutation. Modern advances in gene regulation via epigenetic phenomena will be a central theme, focusing on chromatic remodeling, gene silencing and RNA interference as they pertain to organism development, with an emphasis on plants.
Prerequisite(s): MBG*3040
Department(s): Department of Molecular and Cellular Biology
MBG*4160 Plant Breeding F (3-2) [0.50]
This course examines the application of genetic principles to plant improvement. Topics include breeding objectives, mating systems, selection, testing and germplasm maintenance of horticultural and crop plants.
Prerequisite(s): (MBG*2040 or MBG*2400), STAT*2040
Department(s): Department of Plant Agriculture
MBG*4240 Applied Molecular Genetics in Medicine and Biotechnology W (3-0) [0.50]
This course will examine advanced techniques and methods used in molecular biology, medicine and biotechnology such as genome, transcriptome and proteome analysis, contemporary genetic screens, genetic engineering, transgenic organisms and gene therapy. The course will highlight the most recent developments and applications of such techniques.
Prerequisite(s): MBG*3040
Department(s): Department of Molecular and Cellular Biology
MBG*4270 DNA Replication, Recombination and Repair W (3-0) [0.50]
This course will examine the DNA transactions that determine the structure and function of the genome, with an emphasis on natural and synthetic mutagens and their mode of action, replication and recombination of genetic material, recognition and repair of DNA damage, and inherited and somatic genetic diseases arising from abnormal DNA metabolism.
Prerequisite(s): MCB*2050
Department(s): Department of Molecular and Cellular Biology
MBG*4300 Plant Molecular Genetics F (3-0) [0.50]
This course studies the molecular genetics of plants. The topics include: plant genome diversity and synteny; Arabidopsis thaliana genome, hormonal, environmental and developmental regulation of gene expression; chloroplast and mitochondrial genomes; and gene expression and silencing in transgenics. The course will be delivered using a lecture and paper discussion format. Students will learn and use a variety of computer techniques to search and analyze plant genome databases.
Offering(s): Offered in odd-numbered years.
Prerequisite(s): MBG*2040 or MBG*2400
Department(s): Department of Plant Agriculture
University of Guelph
50 Stone Road East
Guelph, Ontario, N1G 2W1
Canada
519-824-4120