Vaccine Antigens for Necrotic Enteritis of Poultry


Two antigens HP and PFOR, each demonstrated moderate protection for poultry in challenge studies of Necrotic Enteritis (NE). HP and PFOR are proteins linked to the pathogenicity of Clostridium perfringens, the causative agent of NE in poultry, which costs the global poultry industry US $5-6B annually, or $0.05-$0.15 per chick sold. These antigens were developed by Dr. John Prescott and may be useful in the development of an improved multi-antigen vaccine, when combined with the best known protective antigens to date.  

Potential Market

Intensified poultry production – especially broilers 

Research Status

  • Technology readiness level 3
  • Preliminary vaccine tested in poultry 
  • Seeking additional industry and academic partners to collaborate with the University of Guelph and Agriculture & Agri-food Canada.
  • Additional antigens needed to improve efficacy

Patent Status

US 8,501,190 

License Status

Seeking licensee. 


David Hobson, 519-824-4120 x58859