Fluorescent Bioassay Signal Amplification

Technology

• Combination of substrate and reagent that amplifies bioassay fluorescence signals, lowering the limit of detection by an order of magnitude or more relative to ELISA.
• Reagent and substrate compatible with standard bioassay bioreagents and probes.

Applications and Advantages

• Useful for R&D requiring highly sensitive bioassays, e.g. target molecules with extremely low concentrations / sample volumes.
• No complex equipment required, the substrate and reagent can be used with standard microscopes and bioassay techniques.
• Reagent amplifies signals without requiring direct a chemical linkage to a fluorescent probe. 
• Demonstrated success in detecting cancer derived extracellular vesicles.

Status

Provisional utility patent application pending in the US.

Seeking licensee(s).

Contact

Michael Fowler, michaelf@uoguelph.ca, 519-824-4120 x53808