An appreciation course designed primarily for non-biology students. Genetics in life processes, as well as ethical, political, and social interrelations. The course includes sections on eugenics, mutagens, DNA, race differences, sex, multiple births, inheritance of IQ and personality traits, and medicolegal application. Department of Molecular Biology and Genetics.

Fundamental aspects of genetics including the chromosomal basis of inheritance, cytogenetics, genes in populations and quantitative traits. Additional topics include extranuclear inheritance, human genetics, bacterial and viral genetics. The molecular nature of the gene and general mechanisms of gene expression will be introduced but not covered in detail as these topics are expanded in 40-202. Intended as the foundation course in genetics for science students and is a prerequisite for all upper level courses in molecular biology and genetics including 40-202. Department of Molecular Biology and Genetics.

Introduction to the processes by which genetic information is stored, replicated, and expressed in living organisms and the experimental techniques used to study these processes. DNA, gene-protein relationships, and the genetic code. Replication, chromosomes, transcription, and translation. Techniques employed in molecular cloning and applications. Department of Molecular Biology and Genetics.

This course is designed to explore the concepts of random mating, inbreeding, random drift, assortative mating and selection as they relate to natural populations. The dynamic genetic structure of populations and its relationship to the process of speciation is examined. The role and significance of molecular genetics as it relates to population genetics, evolution, systematics and phylogeny is also considered. Department of Zoology.

Chromosome structure and behaviour in plants and animals. Includes discussions on meiosis, chromosomal aberrations, syndromes, polyploidy. Department of Molecular Biology and Genetics. (Offered in odd-numbered years.)

A course designed to introduce the student to the study of biological inheritance in humans. The course includes discussion of the genetic basis of human individual differences, gene frequencies in human populations, human behavioral genetics, human cytogenetics, biochemical genetics and developmental genetics, medical genetics and other aspects of human heredity. Department of Molecular Biology and Genetics.

The nature of Mendelian inheritance when extended to quantitative traits that are jointly influenced by the environment and the simultaneous segregation of many genes. Prediction of response to natural and artificial selection in populations. Department of Animal and Poultry Science.

Bacterial mutations, transformation, transduction, conjugation, recombination, plasmids, transposable elements, gene cloning and the control of genetic expression in bacteria and their viruses. This course is restricted to students in the B.Sc. specialized honours program in Microbiology and to Genetics majors, unless approval by the course instructor is obtained. Department of Microbiology.

Lecture portion only of 40-307. Department of Microbiology.

The basis of, and methods for, effective use of modern animal breeding tools for practical improvement of livestock species. An examination and comparison of the structure of genetic improvement programs across species. International aspects and challenges to animal breeding programs. (First offering F97.)

Reproduction in plants, genetic and cytogenetic structure of plants, nature of phenotypic variability in plants, patterns of response to selection in plant populations, measurement of continuous and discontinuous genetic variability in plant populations. Department of Crop Science.

An examination of the ethical, social, and political issues arising from genetic manipulation, reproductive intervention and biotechnology through the joint application of principles of modern genetics and moral philosophy. Topics include eugenics, cloning, surrogate parenting, abortion, gene therapy, DNA fingerprinting and genetic diagnosis. Related issues such as scientific freedom, access to genetic information and public policy are also considered. Department of Molecular Biology and Genetics. (Offered in even-numbered years.)

An examination of the genetic mechanisms which specify organismic development. Molecular biology of determination and cell differentiation, homeotic genes, oncogenes, genetic control of morphogenesis and pattern formation. Application of embryo manipulation techniques in basic science and medicine. Department of Molecular Biology and Genetics. (Offered in even-numbered years.)

A critical review of genetic methodologies employed in higher eukaryotes and how formal genetic analysis can be integrated with molecular genetics in studying diverse biological research areas such as meiotic recombination, DNA repair, embryonic development, transposable elements and neurobiology. Department of Molecular Biology and Genetics. (Offered in even-numbered years.)

Lecture portion only of 40-404. (Offered in even-numbered years.)

Lecture and demonstration portion only of 40-409. Department of Molecular Biology and Genetics.

The chemical nature of genetic material, transcription and the control of gene expression. DNA cloning and the use of recombinant DNA molecules in modifying gene expression. Department of Molecular Biology and Genetics.

Application of genetic principles to plant improvement. Topics include breeding objectives, mating systems, selection, testing and germplasm maintenance of horticultural and crop plants. Department of Horticultural Science and Department of Crop Science.

Theoretical and scientific aspects of practical animal breeding programs which lead to genetic improvement of efficiency and profitability of animal production. Integrates quantitative genetics with concepts of statistics, economics, biology and biotechnology and expands into development of practical breeding plans. Department of Animal and Poultry Science.

Lecture and demonstration portion only of 40-425. Department of Molecular Biology and Genetics.

The use of molecular genetic techniques to study a wide range of biological problems. Molecular and cellular aspects of biotechnology. In vitro methods of manipulations of animal and plant cells. Genetic engineering in eukaryotes and development of transgenic organisms. Methods of gene therapy and molecular biology of cancer and its treatment. Department of Molecular Biology and Genetics.

DNA replication, recombination and repair. Mechanisms of mutation and relation to carcinogenesis. Methods for detection of environmental mutagens and risk assessment. Department of Molecular Biology and Genetics.

Lecture portion only of 40-426. (Offered in odd-numbered years.)

Structure and evolution of macromolecules and computational analyses of their sequences. Structural studies by physical and chemical approaches of nucleic acid protein complexes associated with gene expression. Department of Molecular Biology and Genetics. (Offered in odd-numbered years.)

Independent theoretical and laboratory research on a topic in the discipline under the supervision of individual faculty. Selection of a faculty supervisor and approval of course coordinator must be obtained before preregistration. This is a double-weighted course. When you select it, you must list both 40-4501 and 40-4502 in the same semester.

Independent theoretical and laboratory research on a topic in the discipline under the supervision of individual faculty. Selection of a faculty supervisor and approval of course coordinator must be obtained before preregistration. This is a double-weighted course. When you select it, you must list both 40-4511 and 40-4512 in the same semester.

Cellular programs in the nuclear cycle of cell proliferation, including cytoplasmic control of DNA replication, chromosome condensation, histone phosphorylation; organization of chromatin, chromomere, telomere, centromere and nucleolus. Related cell fractionation and electron microscopic techniques are included in the laboratory. Department of Molecular Biology and Genetics.