This course will establish the scientific principles underlying the toxic actions of various substances and will introduce the various challenges within the field of toxicology. The chemical nature of injurious substances, their uptake and metabolism by non-target organisms, and their mode of toxic action will be studied in addition to the methods used in safety evaluations and risk assessment. Department of Biomedical Sciences.

A course in trace analysis designed for students in toxicology and related programs. Analytical techniques of value in analyzing samples of toxicological importance will be presented with emphasis also on sample collection and preparation prior to analysis. Department of Chemistry and Biochemistry.

The chemistry of the natural environment; the influence of pollutants upon the environment, including methods of introduction of pollutants to, and removal of pollutants from, the environment. Department of Chemistry and Biochemistry. Also listed as 19-336.

The toxicology of mammalian body systems: dose-response, mechanisms and systemic sites of action of major groups of chemical toxicants. The course is designed for students majoring in toxicology. Department of Biomedical Sciences.

Evaluation of the pathologic responses of cells and tissues to toxic compounds. The course is designed for students majoring in toxicology. Department of Pathology.

Topics in toxicology will consist of oral and written presentations by students, faculty members, and guest lecturers. The emphasis will be on the broad integrative aspects of toxicology with particular reference to the whole organism and higher levels of natural systems; risk assessment and regulatory toxicology. This course is designed for B.Sc. Honours Toxicology students in their 7th or 8th semester. Departments of Biomedical Sciences and Environmental Biology.

A biologically based, advanced course that will give students working knowledge of current processes and techniques for ecotoxicological risk characterization. The course material will cover the topics of problem definition, dose response characterization, exposure characterization, risk assessment, and risk management decision making. Also listed as 34-455.

The molecular mechanisms of action of carcinogens and other toxic compounds. Enzymes of biotransformation, including a detailed study of cytochrome P-450. Interactions of reactive species with DNA and other macromolecules. Designed for students specializing in toxicology, chemistry, or biochemistry. Department of Chemistry and Biochemistry.