University of Guelph 2002-2003 Undergraduate Calendar

XII--Course Descriptions, Chemistry

Department of Chemistry and Biochemistry.

Credit may be obtained in only 1 of CHEM*1040, CHEM*1100; 1 of CHEM*2400, CHEM*2480; 1 of CHEM*2820, CHEM*2880.

*A 1 hour tutorial is scheduled in the third hour of the time slot. Laboratory period extends 3 hours.

Laboratory Deposit: During the first week of classes, a refundable laboratory deposit of $10.00 will be collected from each student who registers in any of the courses in Chemistry, designated below by the symbol "+". Breakages will be charged against this deposit.

CHEM*1040 General Chemistry I F,W(3*-3) [0.50]

A course which introduces concepts of chemistry, the central link between the physical and biological sciences. Principles discussed include chemical bonding simple reactions and stoichiometry, chemical equilibria and solution equilibria (acids, bases, and buffers)..

Prerequisite(s): OAC or equivalent Chemistry or CHEM*1060

Restriction(s): CHEM*1100, CHEM*1300

CHEM*1050 General Chemistry II S,F,W(3*-3) [0.50]

An introductory study of the fundamental principles governing chemical transformations: thermodynamics (energy, enthalpy, and entropy); kinetics (the study of rates of reactions); and redox/electrochemistry.

Prerequisite(s): CHEM*1040 or IPS*1100

Restriction(s): CHEM*1300, CHEM*1310

CHEM*1060 Introductory Chemistry F(3-0) [0.50]

A course stressing fundamental principles of chemistry, designed for students without OAC Chemistry or equivalent. Topics include: atomic theory, the periodic table, stoichiometry, properties of gases and liquids, acid-base concepts and chemical equilibria. This course is intended only for students who require the equivalent of OAC Chemistry in order to proceed to CHEM*1040 or CHEM*1300.

CHEM*1100 Chemistry Today F(3-0) [0.50]

A chemistry course for non-scientists. This course will outline the involvement of chemistry in our daily lives and will provide an appreciation of chemistry from atoms to important complex molecules. Topics will include energy sources, air and water pollution, natural and synthetic polymers, household chemicals, foods, drugs and biochemicals.

CHEM*1300 Introductory Environmental Chemistry F(3*-3) [0.50]

This course presents the fundamentals of chemistry in the context of the environment in the modern industrial world. The core content includes general chemical principles such as stoichiometry, equilibrium and reaction energetics, illustrated with cases and examples that relate these principles to contemporary environmental problems.

Prerequisite(s): OAC Chemistry or CHEM*1060

CHEM*1310 Introductory Environmental Chemistry II W(3*-3) [0.50]

This course extends the foundation of general and physical chemistry for environmental sciences to provide a basis for the understanding of the dynamic behaviour of chemical systems in the external world. The core content includes principles of thermodynamics, photochemistry, electrochemistry and kinetics, illustrated with cases and examples that relate these principles to contemporary environmental problems.

Prerequisite(s): CHEM*1300

CHEM*2060 Structure and Bonding F(3-2) [0.50]

Applications of symmetry, simple crystal structures and principles of bonding. Molecular orbital theory is used to explain the fundamental relationship between electronic and molecular structure. This course provides the elementary quantum background for an understanding of the electronic structures of atoms and molecules.

Prerequisite(s): CHEM*1050, MATH*1210, PHYS*1010

CHEM*2070 Structure and Spectroscopy S,W(3-2) [0.50]

An introduction to spectroscopy and its relationship to molecular structure and dynamics. Rotational, vibrational, electronic and magnetic resonance spectroscopies will be studied. Concepts introduced in CHEM*2060 will be applied to chemical and biochemical problems through spectroscopic techniques. Central to this course is the use of spectroscopy for the determination of molecular structures and the investigation of molecular motions.

Prerequisite(s): CHEM*2060

CHEM*2300 Chemical Reactivity F(3*-3) [0.50]

A general coverage of the reactivity of the elements and some of their compounds, with an emphasis on the compounds of carbon.

Prerequisite(s): CHEM*1050 or CHEM*1310

CHEM*2400 Analytical Chemistry I S,F,W(2-6) [0.75]

Quantitative analysis of important inorganic species in solution by volumetric, gravimetric and spectrophotometric techniques. Spreadsheet applications to solution equilibria and data analysis. This course is intended to build the foundations of good analytical laboratory practice.

Prerequisite(s): CHEM*1050 or IPS*1200

Restriction(s): CHEM*2480

CHEM*2480 Analytical Chemistry I S,F,W(2-3) [0.50]

Same as CHEM*2400 with a 3 hour laboratory component.

Prerequisite(s): 1 of CHEM*1050, CHEM*1310, IPS*1200

CHEM*2580 Introductory Biochemistry S,F,W(3-3) [0.50]

The evolution, chemical structure, and biological roles of the major molecular components of the cell: proteins, nucleic acids, lipids, and carbohydrates, enzymology, intermediary metabolism, with emphasis on catabolic processes.

Prerequisite(s): CHEM*1050 or CHEM*2300

CHEM*2700 Organic Chemistry I S,W(3*-3) [0.50]

An introduction to organic chemistry, stereochemistry, discussion of the major mechanisms and related reactions: nucleophilic substitution and elimination, electrophilic addition, free radical reactions, electrophilic aromatic substitution, nucleophilic addition and nucleophilic acyl substitution.

Prerequisite(s): CHEM*1050

Restriction(s): CHEM*2300

CHEM*2820 Thermodynamics and Kinetics F(3-3) [0.50]

The laws and applications of chemical thermodynamics and chemical kinetics.

Prerequisite(s): CHEM*1050, (MATH*1200 or MATH*2080)

CHEM*2880 Physical Chemistry F(3-2) [0.50]

A survey course for students who are not specializing in chemistry, biochemistry or chemical physics. Topics include basic thermodynamics, chemical equilibrium, macromolecular binding, chemical kinetics, enzyme kinetics, transport processes, colligative properties and spectroscopy. This course describes macroscopic observable properties of matter in terms of molecular concepts.

Prerequisite(s): CHEM*1050, (1 of MATH*1000, MATH*1080, MATH*1200)

Restriction(s): CHEM*2820

CHEM*3360 Environmental Chemistry and Toxicology S,W(3-0) [0.50]

The chemistry of the natural environment; the influence of pollutants upon the environment, including methods of introduction of pollutants to, and removal of pollutants from the environment. (Also listed as TOX*3360.)

Prerequisite(s): CHEM*1050

Equate(s): TOX*3360

Restriction(s): CHEM*1310

CHEM*3430 Analytical Chemistry II: Instrumental Analysis S,W(3-3) [0.50]

Methods for the separation, identification and quantification of substances in the solid, liquid and vapour states. Emphasis will be placed on modern instrumental methods and trace analysis.

Prerequisite(s): CHEM*2400 or CHEM*2480

Co-requisite(s): CHEM*2070

Restriction(s): CHEM*3450, CHEM*3460, TOX*3300

CHEM*3440 Analytical Chemistry III: Analytical Instrumentation F(3-3) [0.50]

Analytical Instrumentation, data acquisition, processing and applications in Chemistry and Biochemistry.

Prerequisite(s): CHEM*3430

Restriction(s): CHEM*3450, CHEM*3460

CHEM*3560 Structure and Function in Biochemistry F,W(3-0) [0.50]

This course develops the understanding of biochemical processes, by examining the enzymatic molecular mechanisms underlying specific cellular and physiological systems. Examples may include oxygen binding/transport and the evolution of globin genes/proteins; regulation of carbohydrate and lipid metabolism; proteins that change shape, including enzymes, membrane proteins, and prion proteins, blood clotting; neurotransmission.

Prerequisite(s): CHEM*2580

CHEM*3570 Analytical Biochemistry S,F(3*-3) [0.50]

The tools and techniques by which biological molecules are isolated, separated, identified, and analyzed. Detailed discussion of experimental methods for macromolecule purification characterization.

Prerequisite(s): (CHEM*2400 or CHEM*2480), CHEM*2580

Restriction(s): MICR*3110

CHEM*3640 Chemistry of the Elements I F(3*-3) [0.50]

A comprehensive introduction to concepts used by inorganic chemists to describe the structure, properties, and reactivity of compounds of the main group elements. The most important concepts covered are: Electronic Structure of Atoms, Symmetry, MO theory, Acids and Basis, Structure of Solids, Trends in the Periodic System.

Prerequisite(s): CHEM*2070

CHEM*3650 Chemistry of the Elements II W(3*-3) [0.50]

The chemistry and structure of transition metal compounds; electronic spectral and structural properties of transition metal complexes; mechanisms of their substitution and redox reactions. Introduction to organometallic chemistry.

Prerequisite(s): CHEM*3640

CHEM*3750 Organic Chemistry II S,F(3*-3) [0.50]

A continuation of the coverage of fundamental aspects of organic chemistry using an assimilation of carbonyl chemistry, unsaturated systems and carbon-carbon bond forming processes to acquaint students with methods of organic synthesis. Topics also include an introduction to spectroscopic methods for the indentification of organic compunds.

Prerequisite(s): CHEM*2700

CHEM*3760 Organic Chemistry III W(3-3) [0.50]

An in-depth treatment of various aspects of organic chemistry. This will include such topics as the chemistry of heterocycles, bio-organic chemistry, polar rearrangements, organic photochemistry and a detailed discussion of organic spectroscopy.

Prerequisite(s): CHEM*3750, CHEM*2070

CHEM*3860 Quantum Chemistry F(3-1) [0.50]

Elementary quantum mechanics for the understanding of the electronic structure of atoms and molecules.

Prerequisite(s): CHEM*2070, MATH*2170

CHEM*3870 Symmetry and Spectroscopy W(2-3) [0.50]

Elementary group theory with applications to molecular spectroscopy. (Offered in odd-numbered years.)

Prerequisite(s): CHEM*2070

CHEM*4010 Chemistry and Industry W(3-0) [0.50]

This course examines industrial processes for the production of organic and inorganic chemicals. The environmental impact and the challenges of a large-scale operation will be considered alongside the actual chemical processes involved.

Prerequisite(s): (CHEM*2300 or CHEM*2700), (CHEM*3430 or TOX*3300), (MATH*1210 or MATH*2080)

CHEM*4400 Advanced Topics in Analytical Chemistry W(3-0) [0.50]

Recent developments in instrumental methods of chemical analysis. A typical selection will include topics from the areas of surface analysis and the applications of lasers in chemical analysis.

Prerequisite(s): CHEM*3430 or CHEM*3450

CHEM*4520 Metabolic Processes F(3-0) [0.50]

An in-depth study of the role of bioenergetics, regulation, and chemical mechanisms in carbohydrate, lipid, and nitrogen metabolism.

Prerequisite(s): CHEM*3560 or CHEM*3570

CHEM*4540 Enzymology W(2-4) [0.50]

A laboratory-intensive course. Enzyme active sites and the mechisms of enzyme action; enzyme kinetics and regulation; recombinant proteins and site-directed mutagenesis as tools for understanding enzymes.

Prerequisite(s): CHEM*3560 (may be taken concurrently), CHEM*3570

CHEM*4550 Biochemistry and Structure of Macromolecules F(3-0) [0.50]

Structure, function, and physical conformation of proteins and nucleic acids, biophysical and computational techniques for the study of biological macromolecules.

Prerequisite(s): (CHEM*3570 and 1 of CHEM*2820, CHEM*2880) or (CHEM*3560, PHYS*3240)

CHEM*4570 Applied Biochemistry F(3-0) [0.50]

Biochemical engineering of the pathways for production of amino acids, antibiotics, proteins, enzymes, and antibodies for applications in industry, medicine and scientific research.

Prerequisite(s): CHEM*3560 or CHEM*3570

CHEM*4580 Membrane Biochemistry W(3-0) [0.50]

An examination at the molecular level of structure and functions of cell membranes, cell surfaces and associated structures. Topics may include: membrane lipids; membrane protein structure; membrane transporters; ATP production; cytoskeleton; cell surface carbohydrates; membrane biogenesis; signal transduction.

Prerequisite(s): CHEM*3560 or CHEM*3570

CHEM*4620 Advanced Topics in Inorganic Chemistry F(3-0) [0.50]

A contemporary treatment of subjects of current interest in modern inorganic chemistry. Possible topics include solid state chemistry and organometallic chemistry.

Prerequisite(s): CHEM*3650

CHEM*4630 Bioinorganic Chemistry W(3-0) [0.50]

The role and importance of transition metal systems in biological processes. (Offered in odd-numbered years.)

Prerequisite(s): CHEM*2580, CHEM*3650

CHEM*4720 Organic Reactivity W(3-0) [0.50]

Introduction to physical organic chemistry, including discussion of reactive intermediates, substituent effects, medium effects, the mechanisms of organic reactions and the theoretical description of the bonding in organic molecules. (Offered in even-numbered years.)

Prerequisite(s): CHEM*3760 (may be taken concurrently)

CHEM*4730 Synthetic Organic Chemistry F(3-0) [0.50]

Introduction to synthetic organic chemistry, including discussion of retrosynthetic analysis, natural products and organic reactions. The integration of these topics for the rational design of synthetic schemes will also be discussed.

Prerequisite(s): CHEM*3760

CHEM*4880 Topics in Advanced Physical Chemistry W(3-0) [0.50]

Selected topics in advanced physical chemistry. (Offered in even-numbered years.)

Prerequisite(s): (CHEM*2820 or PHYS*3240), (CHEM*3860 or PHYS*3230)

CHEM*4900 Chemistry and Biochemistry Research Project I S,F,W(0-9) [0.75]

Research project and seminar in chemistry and biochemistry. This course is designed to provide senior undergraduates with an opportunity to conduct research in an area of chemistry or biochemistry. Students must make arrangements with both a faculty supervisor and the course coordinator prior to registration. Students cannot choose a supervisor with whom they already have research experience in another capacity (e.g. a summer research position). Students should note that most projects are of two semesters' duration, and should plan their studies on the expectation that they will also register in CHEM*4910 in a subsequent semester.

Prerequisite(s): 5.00 credits in chemistry or biochemistry including 1.50 credits from (CHEM*3430 or CHEM*3450), CHEM*3570, CHEM*3640, CHEM*3650, CHEM*3760, CHEM*3870, CHEM*4540

CHEM*4910 Chemistry and Biochemistry Research Project II S,F,W(0-9) [0.75]

Research project and seminar in chemistry or biochemistry. Students must make arrangements with both a faculty supervisor and the course coordinator prior to registration.

Prerequisite(s): CHEM*4900



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