Barth Syndrome Foundation: 2018 BSF Research Grant Program

Sponsor

The Barth Syndrome Foundation, Inc. (BSF)

Program

2018 BSF Research Grant Program

For More Information

Barth Syndrome Foundation Website

Description

The Barth Syndrome Foundation, Inc. (BSF) and its international affiliates announce the availability of funding for basic science and clinical research on the natural history, biochemical basis, and treatment of Barth syndrome. Barth syndrome (BTHS) is a serious X-linked genetic condition associated with cardiomyopathy, neutropenia, skeletal muscle weakness, exercise intolerance, growth delay, and diverse biochemical abnormalities (including defects in mitochondrial metabolism and phospholipid biosynthesis).

BSF is interested in providing “seed grant funding” to young investigators as well as attracting experienced investigators new to the field of Barth syndrome basic science or clinical research. BSF anticipates that these funds will be used for the testing of initial hypotheses and the collection of preliminary data leading to successful long-term funding by the National Institutes of Health (NIH) and other major granting institutions around the world.

Although BSF will consider any research proposal related to Barth syndrome, it is particularly interested in supporting research in the areas identified by Request for Applications (RFAs) that are posted on its website. RFAs for work in clinical/scientific areas that BSF considers to be high priority areas of investigation may have increased budgetary maximums and other requirements. Applications responding to RFAs will be given preferential consideration in the BSF Research Grant Program.

High priority areas of investigation for BSF include:

  • Sudden death/arrhythmias in Barth syndrome
  • Mental and behavioral health issues, such as depression, in Barth syndrome
  • Gastrointestinal pathophysiology in Barth syndrome

Eligibility

BSF's Research Grant Program requires all applicants to be independent investigators (e.g., faculty appointment). Postdoctoral fellows cannot apply. BSF allows young, non-tenured investigators to include in their submitted budget up to 75% of the total grant amount as PI salary. In addition, for those clinical applications where volunteers must travel to a clinical research site, these travel expenses will be handled separately and will be excluded from the budget maximums mentioned above. We encourage independent investigators at all professional levels to submit their best ideas. There are no geographical limitations to this funding. 

Maximum Project Value

Idea Grants: $50,000 USD
Development Grants: $100,000 USD

Indirect Costs

10%

Project Duration

Idea Grants: one - two years
Development Grants: two - three years

Special Notes

Note: Applicants invited to the full application stage (or in cases where the LOI is not mandatory), must build in time to ensure a hard copy of the full application, that includes the applicant's signature as well as the institutional signature, is mailed to and received by BSF by the deadline of October 31, 2018. 

The address for submitting the full application is as follows. Please note, it is the responsibility of the applicant to ensure the full application is received, both electronically and by hard copy mail, by the deadline of October 31, 2018. 

Matthew J. Toth
PhD Science Director
Barth Syndrome Foundation, Inc.
132 Creemer Avenue
Iselin, NJ 08830 USA

Note: This is a competitive grant program with a historical 30% success rate in receiving funding.

Deadlines

If College-level review is required, your College will communicate its earlier internal deadlines.

TypeDateNotes
External Deadline

The one-page Letter of Intent (LOI) is due directly to the BSF Science Director (matthew.toth@barthsyndrome.org). See the 'How to Apply' section for more details on the LOI and to determine what streams require mandatory LOI's . 

Internal Deadline

(If invited or if LOI was not mandatory): Full Application, including budget, OR-5 and signature from applicant, must be submitted to research.services@uoguelph.ca a minimum of 2-weeks prior to the deadline to submit the application package to the sponsor. This deadline is set to allow for time for the applicant to mail a hard copy of the application (including the institutional signature) directly to BSF. 

External Deadline

Completed Full Application must be submitted directly to the BSF Science Director (matthew.toth@barthsyndrome.org), both electronically and by mail (see 'Special Notes' section for more details). Funds will be available to successful grant applicants after they have been notified in late February, 2019. 

How to Apply

Letter of Intent (LOI): The letter of intent is a one-page document describing the applicant’s research plan/idea in applying for funding. The letter of intent is mandatory for Development grant applications and mandatory for applications answering specific Request For Applications (RFAs) advertised by the BSF Research Grant Program. The letter of intent is optional for Idea grant applicants who would like to receive feedback from BSF​.

Full Application (If invited or if LOI not mandatory for the application stream): Each grant application must contain the following elements to be considered complete. Please see the 'BSF Grant Guidelines & Policies' in the File Attachment document for complete information.

  • A completed Information Form
  • A Summary/Abstract
  • Specific Aims
  • Relevance to Barth Syndrome
  • Research Strategy
  • Plans for longer-term funding
  • References
  • Biographical Sketch
  • Budget Form/Table
  • External reviewers to include/exclude
  • Statement of human subjects or vertebrate animal use
  • Resources and Environment
  • Project personnel

Attachment(s)

For Questions, please contact

Matthew J. Toth, PhD
Science Director
Barth Syndrome Foundation, Inc.
matthew.toth@barthsyndrome.org
bsfinfo@barthsyndrome.org
Toll Free: 855-662-2784 (855-NO-BARTH)
Local Line: 914-303-6323

Office of Research

Amy Bossaer, Senior Grants and Contracts Specialist
Office of Research Services
519-824-4120 x58613
abossaer@uoguelph.ca

Alert Classifications
Category:
Funding Opportunities and Sponsor News

Disciplines:
Health and Life Sciences