Canadian Cancer Society Breakthrough Team Grants: Transforming the Future of Metastatic Cancer


Canadian Cancer Society

For More Information

See CCS's Website for full program and application information.


The intent of the Canadian Cancer Society (CCS) Breakthrough Team Grants model is to bring together passionate and talented teams of scientists, clinicians, patient partners, and knowledge users from across disciplines to work synergistically and ‘think big’ to address important gaps in cancer research that will be transformational for people affected by the disease. 

The primary scientific objectives for this Breakthrough Team Grants program are twofold (and intended to be represented by at least 2 funded Breakthrough Teams):

  • Theme 1 – To develop a better understanding of the biology of and mechanisms associated with cancer cell dormancy; and
  • Theme 2 – To better support people living with advanced or metastatic disease throughout the course of their disease.


Teams will be expected to:
  • Be drawn from at least 3 Canadian provinces, (with international collaborations outside of Canada encouraged where expertise is essential).
  • Be multi-disciplinary in composition (research pillar, scientific/clinical focus, discipline) to stimulate diverse approaches to addressing the research question, including how a potential solution could be administered equitably across Canada.
  • Include, as an integral part of the team, clinical and other health professionals, patient partners/people with lived experience (termed patients/survivors/caregivers or PSCs), and knowledge users (such as policy specialists), whose experience and expertise will lend valuable insights to the development and implementation of the project.
  • Include at least one early career investigator as a Co-Principal Investigator, and at least 3 trainees at the Master’s, PhD, or Postdoctoral levels who will be provided with specific training and mentorship (by the team and CCS) throughout the duration of the grant.

Funding Availability

  • Teams may request a maximum of $1.5M per year over 5 years (to a maximum of $7.5M).
  • Funding will be provided to support the direct costs of research, including supplies, salaries and equipment associated with the proposed work. Equipment requests cannot exceed 10% of the requested budget, or $500K, whichever is higher. 
  • Indirect costs are not eligible. 

Indirect Costs



If College-level review is required, your College will communicate its earlier internal deadlines.

External Deadline

CCS's Mandatory Informational & Networking Workshop. Interested applicants must register to attend.

External Deadline

Applicants submit completed LOI to sponsor.

Internal Deadline

Submit complete application with OR-5 form to

External Deadline

Full application due to CCS.

For Questions, please contact

Office of Research

Laurie Gallinger, Awards & Agreements Officer
Research Services Office

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