Cancer Research Society - 2023 Operating Grants


Cancer Research Society (CRS)

For More Information

For additional information, please visit the Cancer Research Society website for

  • program guidelines;
  • application forms;
  • evaluation criteria.


Operating grants are the primary means by which the Cancer Research Society supports fundamental, early translational and environment-cancer research activities on all types of cancer, contributing to the advancement of science aimed at preventing, detecting and treating this disease. The Cancer Research Society Operating Grants Competition is now open to researchers across Canada.

CRS Operating Grants are intended to support Canadian researchers in their pursuit to advance scientific knowledge in the following five (5) areas:

  1. fundamental/basic cancer research;
  2. prevention;
  3. early translational cancer research, including preclinical research, cellular or animal models, biomarkers for diagnostics and prognosis, imaging and treatment;
  4. research studying the environmental causes of cancer includ ing viruses,pollutants, work environment, lifestyle and diet;
  5. in collaboration with CIHR: “Survivorship” research to improve the health outcomes of cancer survivors of all ages, from the time of diagnosis to their end-of-life care, including studies on side effects and comorbidities resulting from cancer therapies.

The following research areas are not eligible for Operating Grants:

  • clinical trials;
  • applied research for the development or improvement of tools such as instruments, medical devices, software, questionnaires, information tools, patient registries, biobanks, TMA collections, etc.;
  • psychosocial or social studies, survivorship, etc.;
  • health care economics, or any study aiming at measuring the use and costs of the health care system;
  • any other type of research not included in the main five funded areas.


All applicants and co-applicants must hold an academic appointment at a Canadian university or accredited institution.

They must have their own laboratory and have the possibility of hiring students and postdoctoral fellows.

A Young Investigator is an independent investigator, who has started their career in a university or research institution within the last five years (i.e. after August 31, 2018). Due to the COVID-19 pandemic, an applicant who has held an Early-career Investigator status as of March 1, 2020 or attained their first academic appointment after this date will be granted a one-year extension of their status.

The following are not eligible:

  • postdoctoral fellows are not eligible;
  • research associates are not eligible;
  • staff and research scientists without an academic appointment.


Maximum Project Value

$62,500/year to max of $125,000 per grant

Indirect Costs


Project Duration

2 years


If College-level review is required, your College will communicate its earlier internal deadlines.

External Deadline

Letter of Intent: Mandatory: PI to submit directly to sponsor

New this year: The main applicant/PI must register at the CRS Research Portal, ProposalCentral. The application process is comprised of two stages:

  1. Letter of Intent (LOI) submission, and if invited; 
  2. Full Proposal submission.

All applicants must submit a LOI that will include a high-level description of their research project goals. Refer to section 5 of CRS Guidelines (attached) for LOI submission instructions. LOIs are reviewed for conformity and quality by CRS at the time of submission. Once the LOI has been reviewed, the applicant will be notified via e-mail as to whether or not they have been invited to submit a Full Proposal. Both LOI must be submitted electronically at the CRS Research Portal, ProposalCentral 

Internal Deadline

Application if Invited: PI to submit a copy of the application along with a complete OR5 form to:

External Deadline

Application if Invited: PI to submit directly to sponsor.  Full Proposal must be submitted electronically at the CRS Research Portal, ProposalCentral 

See section 6 of attached CRS Guidelines for further full proposal application instructions.


PDF icon CRS Program Guidelines 2023236.29 KB
For Questions, please contact

Cancer Research Society


Customer Support Monday through Friday 8:30am - 5:00pm Eastern Time
800-875-2562 (Toll-free U.S. and Canada)

Office of Research

Ornella McCarron, Grants Officer
Research Services Office
519-824-4120 x52832

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