Department of Defense Peer Reviewed Medical Research Program - Investigator-Initiated Research Award 2018


Congressionally Directed Medical Research Programs (CDMRP)


The PRMRP Investigator-Initiated Research Award (IIRA) is intended to support studies that will make an important contribution toward research and/or patient care for a disease or condition related to at least one of the FY18 PRMRP Topic Areas.

The rationale for a research idea may be derived from a laboratory discovery, population-based studies, a clinician’s first-hand knowledge of patients, or anecdotal data.  Applications must include relevant data that support the rationale for the proposed study.  These data may be unpublished or from the published literature.


The vision of the FY18 PRMRP is to improve the health and well-being of all military Service members, Veterans, and beneficiaries.  The PRMRP challenges the scientific and clinical communities to address at least one of the FY18 PRMRP Topic Areas with original ideas that foster new directions along the entire spectrum of research and clinical care.  The program seeks applications in laboratory, clinical, behavioral, epidemiologic, and other areas of research to advance knowledge in disease etiology, improve prevention, detection, diagnosis, treatment, and quality of life for those affected by a relevant disease or condition, and to develop and validate clinical care or public health guidelines.

Key Mechanism Elements 

  • Supports research that will make an original and important contribution to the field of research and/or patient care in the Topic Area(s) of interest
  • Partnering PI Option available
  • Clinical trials will not be funded
  • Preproposal (Letter of Intent) submission is required; application submission is by invitation only


Assistant Professor level or above (or equivalent).

Maximum Project Value

Maximum funding of $1.2 - $1.5 million U.S. See Funding Restrictions in Program Announcement.

Indirect Costs

10% as per program guidelines.

Project Duration

Maximum period of performance is three years.


If College-level review is required, your College will communicate its earlier internal deadlines.

External Deadline

Pre-Application (LOI) due to sponsor through online portal.

Internal Deadline

If invited to full-proposal, please notify Kristin Gibson by email.  The full proposal and OR-5 are due to two weeks in advance of the external deadline to allow for review and compilation of supporting documents.

External Deadline

Application due to sponsor through online portal.  Office of Research Services staff to submit on behalf of the PI.

How to Apply

Please see: Funding  Opportunity Number: W81XWH18PRMRPIIRA

For Questions, please contact

For Agency Contacts please see Section E - DoD General Application Instructions​.

Office of Research

Kristin Zimmermann, Senior Grants & Contracts Specialist
Research Services Office
519-824-4120 x56257

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