Ontario Institute for Cancer Research (OICR), Cancer Therapeutics Innovation Pipeline – Request for Applications 2022

Updated Information

New external deadline for Letter of Intent – see "Deadlines" below for details:

  • from Wednesday, July 13, 2022 to Thursday, July 14, 2022 at 5 pm.


Ontario Institute for Cancer Research (OICR).


Cancer Therapeutics Innovation Pipeline

For More Information

For complete program details and how to apply, please visit the Cancer Therapeutics Innovation Pipeline program web-page.


The Cancer Therapeutics Innovation Pipeline (CTIP) Program was established to capitalize on Ontario’s expertise in cancer biology and drug discovery. Its aim is to create a pipeline of validated cancer targets and first-in-class or best-in-class, novel, selective lead molecules (small molecules or biologics) that will attract partnerships and/or investment for further preclinical and clinical development. To generate a sustainable pipeline, CTIP will support projects that aim to provide increasing evidence of target validation and disease association using data from knowledge bases, functional assays, and drug screening in relevant in vitro and in vivo models of the cancer type of interest.

CTIP funds projects in four stages of preclinical drug discovery and is currently inviting applications for the following two funding streams:

Early Validation (EV) projects:

  • Deliver robust translational evidence that a Target-of-Interest (TOI) is associated with a specific cancer type(s) based on data from knowledge bases and from studies demonstrating that perturbation of the TOI in relevant cell-based models produces anti-cancer effects sufficient to trigger a drug discovery campaign.
  • Funding available: Up to $150,000 per year for a maximum of two years.

Early Accelerator (EA) projects: 

  • Deliver a validated primary assay to enable initial screening of molecules against a defined target.
  • Funding available: Up to $150,000 for a maximum of one year.


OICR invites applications from investigators at Ontario academic centres, hospital research institutes, or other government research institutions. CTIP funding is only tenable in Ontario. For-profit entities are not eligible to apply. 

Investigators are eligible to participate on and submit multiple CTIP submissions. OICR is focused on developing and supporting the next generation of cancer researchers, and strongly encourages applicants to include early career investigators/clinicians as part of the study team.

For complete program eligibility criteria, please visit the Cancer Therapeutics Innovation Pipeline program web-page.

Funding Availability

EV projects will be funded up to $150,000 per year, inclusive of overhead, for a maximum of two (2) years.

EA projects will be funded up to $150,000, inclusive of overhead, for a maximum of one (1) year.

Please note, annual funding is contingent upon available funding from the Government of Ontario via the Ministry of Colleges and Universities.

Indirect Costs

OICR will provide up to thirty per cent with respect to eligible direct research expenses of the approved proposal to cover institutional overhead.

Project Duration

The funding term start date for a funded CTIP application is December 1, 2022:

  • The award term for EV projects is up to two (2) years (December 1, 2022 – November 30, 2024).
  • The award term for EA projects is up to one (1) year (December 1, 2022 - November 30, 2023). 

Special Notes

For an overview of the CTIP funding opportunity, consider attending a one-hour, virtual info session on June 30, 2022, 2-3 p.m. ET. This session will be recorded and posted on the OICR web-page for viewing at a later date. To register for the session, please visit the Session Registration web-page.


If College-level review is required, your College will communicate its earlier internal deadlines.

Internal Deadline

Please submit the completed LOI form along with a signed OR-5 form to research.services@uoguelph.ca.

Please note: A Notice of Intent (NOI) must be submitted prior to gaining access to the full Letter of Intent (LOI) form. The information provided in the NOI can be updated prior to submitting the LOI. The deadline for submission of the NOI is the same as the deadline for LOI submission; however, applicants are encouraged to submit their NOI as early as possible to assist with planning.

External Deadline

Applicant to submit LOI using OICR's Grant Management System, ReportNet. 

The LOI results will be communicated by August 22, 2022. Qualified applicants will be invited to submit a full application. Please inform research.services@uoguelph.ca if you are invited to submit a full application.

Internal Deadline

Please submit the full application package to research.services@uoguelph.ca

External Deadline

Applicant to submit full application using OICR's Grant Management System, ReportNet. 

If successful, applicants will be notified by December 2022.

How to Apply

NOIs, LOIs and full applications are to be submitted using ReportNet, OICR’s online system for managing grants and awards. 

For complete details on how to apply, please visit the Cancer Therapeutics Innovation Pipeline program web-page.
For Questions, please contact

Please refer to the FAQ page before contacting the OICR Scientific Secretariat office at ScientificSecretariat@oicr.on.ca.

Office of Research

Vanessa Knox, Awards and Agreements Officer
Research Services Office
519-824-4120 x53429

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