Grand Challenge: Innovations in Vaccine Manufacturing for Global Markets


Bill & Melinda Gates Foundation


Grand Challenge: Innovations in Vaccine Manufacturing for Global Markets

For More Information

For additional information, please visit the program’s website for:


This challenge focuses on innovations in vaccine manufacturing platforms designed to lower production cost for vaccines that target diseases of great global burden and that are among the most costly to produce with current technologies. The proposed research and development will focus on at least one of the following: human papillomavirus, inactivated poliovirus, measles-rubella, pentavalent, pneumococcal, or rotavirus vaccine. The ultimate goal of this challenge is to significantly increase global access to priority vaccines by lowering the manufacturing cost required to produce them.


Grand Challenges is open to both foreign and domestic organizations, including non-profit organizations, for-profit companies, international organizations, government agencies and academic institutions.

Funding Availability

The foundation will not provide specific funding limits or expectations. The number of awards and quantity of each award amount will depend upon the quality of the proposals received. Proposers are expected to develop a budget commensurate with the scope and scale of the work necessary to achieve the objectives laid out therein.

Indirect Costs


Project Duration

5 years


If College-level review is required, your College will communicate its earlier internal deadlines.

Internal Deadline

Please submit your application/proposal, along with an OR-5 Form to

External Deadline

How to Apply

LOIs are invited for submission through the foundation’s Unison Portal (applicants must first create a log-in for Unison), RFP number SOL1139572. The application process will require the proposer to agree to the Website Terms of Use and Privacy Policy, and acknowledge that any information provided (either orally or in writing) will be subject to and handled in accordance with such provisions. This request for proposals will make use of a two-step application process: Step 1: LOI Submission and Step 2: Invited Full Proposals. 


For Questions, please contact 

Office of Research

Katie Meyer Beck, Director, Research Support Services
Research Services Office
519-824-4120 x54059

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