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  2. Cortland Griswold

Cortland Griswold

Cortland Griswold

Associate Professor

College of Biological Science, Department of Integrative Biology

cgriswol@uoguelph.ca
Office:SC1 Room 1474
Google Scholar
Phone:
ext. 56240
Lab:
1409/10

Research Areas

  • Evolutionary biology

Education

  • B.Sc. – University of Wisconsin-Madison
  • M.Sc. – University of Toronto
  • Ph.D. – University of British Columbia

Research

Theoretical Evolutionary Genetics, including

  • Ancestral graph theory
  • Polyploid population genetics
  • Other topics in support of students

Select Publications

More recent representative papers

  • Ge, X., Newman, J.A. and C.K. Griswold. 2024. Geographic variation in evolutionary rescue under climate change in a crop pest–predator system. Evolutionary Applications 17: e13750.
  • Chernomas, G. and C.K. Griswold. 2024. Deleterious mutation/epimutation–selection balance with and without inbreeding: a population (epi)genetics model. Genetics 227: iyae080.
  • Griswold, C.K. and S. Asif. 2024. Correction: Meiosis at three loci in autotetraploids: Probabilities of gamete modes and genotypes without and with preferential cross-over formation. Heredity 132: 331 - 333.
  • Verweij, W. and C.K. Griswold. 2023. Spatial structure and benefits to hosts allow plasmids with and without post-segregational killing systems to coexist. Biology Letters 19: 20220376.
  • Griswold, C.K and S. Asif. 2023. Meiosis at three loci in autotetraploids: Probabilities of gamete modes and genotypes without and with preferential cross-over formation. Heredity 130: 223-235.
  • Griswold, C.K. 2022. A dynamic ancestral graph model and GPU-based simulation of a community based on metagenomic sampling. Molecular Ecology Resources 22: 2429 - 2442.
  • Griswold, C.K. 2021. The effects of migration load, selfing, inbreeding depression, and the genetics of adaptation on autotetraploid versus diploid establishment in peripheral habitats. Evolution 75: 39-55.
  • Mostafaee, M. and C.K. Griswold. 2019. Two-Locus Local Adaptation by Additive or Epistatic Gene Combinations in Autotetraploids Versus Diploids. Journal of Heredity 110: 866-879.
  • Griswold, C.K. 2019. Properties of Samples With Segregating Polymerase Chain Reaction (PCR) Dropout Mutations Within a Species. Evolutionary Bioinformatics 15: 1-15.
  • Griswold, C.K. 2019. An ancestral process with selection in an ecological community. Journal of Theoretical Biology 466: 128 - 144.
  • Griswold, C.K. and M.W. Williamson. 2017. A two-locus model of selection in autotetraploids: Chromosomal gametic disequilibrium and selection for an adaptive epistatic gene combination. Heredity 119: 314-327.

Earlier representative papers

  • Griswold, C.K. 2015. Additive genetic variation and evolvability of a multivariate trait can be increased by epistatic gene action. Journal of Theoretical Biology 387: 241-257.
  • Griswold, C.K. 2015. Epistasis can accelerate adaptive diversification in haploid asexual populations. Proceedings of the Royal Society B 282: 20142648.
  • McKay, P.B. and C.K. Griswold. 2014. A comparative study indicates both positive and purifying selection within ryanodine receptor (RyR) genes, as well as correlated evolution. Journal of Experimental Zoology Part A: Ecological Genetics & Physiology 321: 151-163.
  • Griswold, C.K. and T.A. Henry. 2012. Epistasis can increase multivariate trait diversity in haploid non-recombining populations. Theoretical Population Biology 82: 209-221.
  • Griswold, C.K. and D.J. Eisner. 2012. The mapping of epistatic effects onto a genealogical tree in haploid populations. Theoretical Population Biology 81: 32-44.
  • Griswold, C.K. 2011. A Model of the Physiological Basis of a Multivariate Phenotype that is Mediated by Ca2+ Signaling and Controlled by Ryanodine Receptor Composition. Journal of Theoretical Biology 282: 14-22.

Teaching

  • BIOL*3020 - Population Genetics (Fall 2024)
  • BIOL*4120 - Evolutionary Ecology (Winter 2025)