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  2. Katrina Watson

Katrina Watson

katrinawatson

Research Technician

Ontario Veterinary College, Department of Biomedical Sciences

kawatson@uoguelph.ca
(519) 824-4120, Ext. 54974
Office:OVC Main Animal Holding, Room 3638A
Research Assistant in Dr. Roger Moorehead's lab with research focused on MicroRNAs (miR- 200 family) in mouse models of breast cancer.
Selected Publications
  • Vaz, M., Watson, K. L., & Moorehead, R. A. (2025). Reduced JAG1 Expression Through miR-200 Overexpression or Crispr-Cas Mediated Knockout Impairs TNBC Growth and Metastasis. Molecular carcinogenesis, 64(8), 1392–1407. https://doi.org/10.1002/mc.23937
  • Watson, K. L., & Moorehead, R. A. (2025). Transgenic overexpression of the miR-200b/200a/429 cluster prevents mammary tumor initiation in Neu/Erbb2 transgenic mice. International journal of cancer, 156(5), 993–1004. https://doi.org/10.1002/ijc.35211
  • Simpson, K. E., Staikos, C. A., Watson, K. L., & Moorehead, R. A. (2023). Loss of MXRA8 Delays Mammary Tumor Development and Impairs Metastasis. International journal of molecular sciences, 24(18), 13730. https://doi.org/10.3390/ijms241813730
  • Mahesaniya, A., Williamson, C. R., Keyvani Chahi, A., Martin, C. E., Mitro, A. E., Lu, P., New, L. A., Watson, K. L., Moorehead, R. A., & Jones, N. (2022). Sex Differences in Glomerular Protein Expression and Effects of Soy-Based Diet on Podocyte Signaling. Canadian journal of kidney health and disease, 9, 20543581221121636. https://doi.org/10.1177/20543581221121636
  • Simpson, K. E., Watson, K. L., & Moorehead, R. A. (2022). Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo. Genes, 13(4), 691. https://doi.org/10.3390/genes13040691
  • Watson, K. L., Yi, R., & Moorehead, R. A. (2021). Transgenic overexpression of the miR-200b/200a/429 cluster inhibits mammary tumor initiation. Translational
    oncology, 14(12), 101228. https://doi.org/10.1016/j.tranon.2021.101228
  • Watson, K. L., Sauerzopf, K., & Moorehead, R. A. (2021). Isolated Soy Protein Promotes Mammary Tumor Development Induced by the Type I Insulin-like Growth Factor Receptor in Transgenic Mice. Nutrition and cancer, 73(8), 1340–1349. https://doi.org/10.1080/01635581.2020.1795210
  • Simpson K, Conquer-van Heumen G, Watson KL, Roth M, Martin CJ, Moorehead RA. Re-expression of miR-200s in claudin-low mammary tumor cells alters cell shape and reduces proliferation and invasion potentially through modulating other miRNAs and SUZ12 regulated genes. Cancer Cell Int. 2021 Feb 4;21(1):89. doi: 10.1186/s12935-021-01784-4. PMID: 33541373; PMCID: PMC7863273.
  • Watson, K. L., Jones, R. A., Bruce, A., & Moorehead, R. A. (2018). The miR-200b/200a/429 cluster prevents metastasis and induces dormancy in a murine claudin-low mammary tumor cell line. Experimental cell research, 369(1), 17–26. https://doi.org/10.1016/j.yexcr.2018.04.024