Other Course Description or Assignment Information:
A graduate-level treatment of modern NMR spectroscopy and complementary analytical techniques, with an emphasis on practical structure elucidation of organic molecules.
NMR spectroscopy is among the most powerful tools available for characterising molecular structure, dynamics, and interactions. This course surveys the 1D and 2D NMR experiments commonly used in chemical research, building from a conceptual foundation in nuclear spin, chemical shift, and coupling. Topics include routine NMR experiments, multinuclear NMR, relaxation & molecular dynamics, and diffusion (DOSY), treated at a level appropriate for independent application. IR and mass spectrometry are integrated as complementary tools. Selected advanced topics will also be introduced (e.g. solid-state NMR, quantitative NMR). The focus throughout is on the logic-driven process of structure elucidation, developed through worked examples, case studies, hands-on NMR experience, and integrated problems.
Projected Class Enrolment: