Dr. Everson Nunes

• Postdoctoral Research Fellow - Protein Metabolism - McMaster University
• PhD in Molecular Cell Biology (Physiology), Nutritional Supplements & Immune Function - Universidade Federal do Paraná (UFPR)
• MSc in Molecular Cell Biology (Physiology), Resistance Training & Nutritional Support in Oncology - Universidade Federal do Paraná (UFPR)
• BSc in Human Nutrition - Universidade Federal do Paraná (UFPR)
• BSc in Biological Sciences - Universidade Federal do Paraná (UFPR)

I am particularly interested in the regulation of human metabolism and the metabolic changes caused by disease states, diet, nutritional supplements, and physical activity. Most of my research investigates physiological mechanisms involved in applying dietary and physical activity interventions to prevent and treat chronic diseases (e.g. Cancer, Obesity, Sarcopenia, and Type 2 Diabetes).

I am passionate about understanding and researching human metabolism, with a particular focus on how diet and physical activity influence metabolic changes. My research portfolio includes the prevention and treatment of chronic diseases such as cancer, Type 2 diabetes, and obesity. I specialize in human physiology and nutrition, exploring endocrine physiology, metabolic regulation, and the efficacy of nutritional and exercise-based interventions in treating and preventing chronic diseases. Through my research projects and courses, I aim to advance scientific knowledge and contribute to improved health outcomes.

1. Nunes EA, Colenso-Semple L, McKellar SR, Yau T, Ali MU, Fitzpatrick-Lewis D, et al. Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults. J Cachexia Sarcopenia Muscle. 2022;13(2):795–810. doi: 10.1002/jcsm.12922 PMID: 35156206
2. McGlory C, Calder PC, Nunes EA. The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health, Disuse, and Disease. Front Nutr. 2019;6:144. doi: 10.3389/fnut.2019.00144 PMID: 31781502
3. Nunes EA, Stokes T, McKendry J, Currier BS, Phillips SM. Disuse-Induced Skeletal Muscle Atrophy in Disease and Nondisease States in Humans: Mechanisms, Prevention, and Recovery Strategies. Am J Physiol Cell Physiol. 2022;322(6):C1068–C1084. doi: 10.1152/ajpcell.00511.2021 PMID: 35442247
4. Corrêa CR, Formolo NPS, Dezanetti T, Speretta GFF, Nunes EA. Relative Fat Mass is a Better Tool to Diagnose High Adiposity when Compared to Body Mass Index in Young Male Adults: A Cross-Sectional Study. Corrêa CR, Formolo NPS, Dezanetti T, Speretta GFF, Nunes EA. Clin Nutr. ESPEN. 2021 Feb;41:225-233. doi: 10.1016/j.clnesp.2020.12.009. PMID: 33487268
5. Brunetta HS, de Paula GC, de Oliveira J, Martins EL, dos Santos GJ, Nunes EA. Decrement in Resting and Insulin-Stimulated Soleus Muscle Mitochondrial Respiration is an Early Event in Diet-Induced Obesity in Mice. Exp Physiol. 2019;104(3):306–321. doi: 10.1113/EP087296 PMID: 30485634
6. Smeha L, Fassula AS, Franco Moreno YM, Gonzalez-Chica DA, Nunes EA. Dietary Acid Load is Positively Associated with Insulin Resistance: A Population-Based Study. Clin Nutr ESPEN. 2022;49:341–347. doi: 10.1016/j.clnesp.2022.03.025 PMID: 35623835
7. Brunetta HS, Chagas TR, Fabre MES, Trindade EBSM, Silva ELD, Nunes EA. Fish Oil Decreases the Severity of Treatment-Related Adverse Events in Gastrointestinal Cancer Patients Undergoing Chemotherapy: A Randomized, Placebo-Controlled, Triple-Blind Clinical Trial. Camargo CQ, Mocellin MC, Clin Nutr. ESPEN. 2019 Jun;31:61-70. doi: 10.1016/j.cln sp.2019.02.015. PMID: 31060836
8. Jakubowski JS, Wong EPT, Nunes EA, Noguchi KS, Vandeweerd JK, Phillips SM. Equivalent Hypertrophy and Strength Gains in β-Hydroxy-β-Methylbutyrate- or Leucine-Supplemented Men. Med Sci Sports Exerc. 2018;51(1):65–75. doi: 10.1249/MSS.0000000000001757 PMID: 30113317
9. Corrêa CR, da Costa BGG, Silva KS, Shivappa N, Wirth MD, Hébert JR, Nunes EA. A Higher Energy-Adjusted Dietary Inflammatory Index is Positively Associated with Total and Visceral Body Fat in Young Male Adults. J Hum Nutr Diet. 2022;35(6):1136–1150. doi: 10.1111/jhn.13012 PMID: 35377488
10. Brunetta HS, de Paula GC, Fritzen MS, Cecchini MS, dos Santos GJ, Nunes EA. Leucine Increases Muscle Mitochondrial Respiration and Attenuates Glucose Intolerance in Diet-Induced Obesity in Swiss Mice. J Funct Foods. 2019;62:103544. doi: 10.1016/j.jff.2019.103544 PMID: Not in PubMed

Undergraduate Courses:

• Advisor - KIN 4400: Independent Research Study in Kinesiology (Guelph Humber)

Graduate Courses:

MSc in Human Health and Nutritional Sciences

• HHNS*6930 Research Project (Coursework team-based)

• HHNS*6320 Advances in Human Health and Nutritional Sciences Research (Literature Review - Coursework team-based)

MSc Medical Foundations

• MEDF*6060: Multisystem Human Physiology