Dr. Marica Bakovic
Professor
Email: mbakovic@uoguelph.ca
Office: ANNU 346
Ext: 53764
Lab: ANNU 309
Ext: 56717
Education | Research | Publications | Teaching | Grad Students |
Education
B.Sc. - Belgrade
M.Sc. - Belgrade
Ph.D. - Alberta
Research
Regulation of genes involved in choline transport and phospholipid metabolism; nutrient transporters and kinetics of membrane transport; molecular and cell biology of lipids; the effect of nutrients on protein synthesis and gene expression. Nutritional genomics (nutrigenomics) of risk factors for cardiovascular disease and insulin resistance
Selected Publications
Pavlovic Z, and Bakovic M (2013). Regulation of Phosphatidylethanolamine Homeostasis—The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2). Int J Mol Sci. 14(2):2529-50.
Singh, R K Fullerton, D M, Vine, D and Bakovic, M (2012). Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase (Pcyt2) deficient mice. J Lipid Res 53, 1811-1822.
Duric M, Servanesen S and Bakovic M (2012). Phosphatidylcholine Functional Foods and Nutraceuticals: A Potential Approach to Prevent Non-alcoholic fatty liver disease. European J Lipid Sci Technology 114, 389–398.
Zhu, L and Bakovic, M (2012). Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP: ethanolaminephosphate cytidylyltransferase-Pcyt2 activity. Biochem Cell Biol 90(2):188-99.
Pereira, L, Girardi, JP, and Bakovic, M (2012) Forms, cross-talks, and the role of phospholipid biosynthesis in autophagy. Int J Cell Biol2012:931956.
Bakovic M and Michel V. Eds (2012). Hot Topic Mini-Review Edition on Choline In: "Central Nervous System Agents in Medicinal Chemistry", Bentham Science Publishers. ISSN: 1871-5249.
V Michel, and M Bakovic (2012) The ubiquitous choline transporter SLC44A1. Cent Nerv Syst Agents Med Chem 2012 Apr 2. [Epub ahead of print] PMID: 22483272.
Bakovic M (2011). Different systemic and peripheral ghrelin responses in metabolic disorders. J Pediatr Biochem, Volume 2 , Number 2 Editorial Paper; ISSN: 1879-5390.
Girardi JP, Pereira L, Bakovic M (2011). De novo synthesis of phospholipids is coupled with autophagosome formation. Med Hypotheses, 77(6):1083-7.
Michel, V., R. K. Singh, and M Bakovic (2011). The impact of choline availability on muscle lipid metabolism. Food & Function 2(1): 53-62.
J. Tucker, B. Deschambault and M. Bakovic (2011). Nutritional Genomics: Fundamental Role of Diet in Chronic Disease Prevention and Control. "Functional Foods, Nutraceuticals and Degenerative Disease Prevention” (Palyath, Bakovic, and Shetty Eds.); John Walley and Sons p. 45-67.
Gopinadhan P., M Bakovic and K Shetty Eds (2011). Book: “Functional Foods, Nutraceuticals and Degenerative Disease Prevention”, John Walley and Sons. Inc. p.403.
Fullerton M and M Bakovic (2010). Complementation of the metabolic defect in CTP: phosphoethanolamine cytidylyltransferase (Pcyt2) deficient primary hepatocites. Metabolism 59(12):1691-700.
Teaching
HHNS*6440 Nutrition and Gene Expression
NUTR*4360 Current Issues in Nutrigenomics
Grad Students
P. Basu (PhD student)
Z. Pavlovic (PhD student)
L. Schenkel (PhD student)
A. Chang (MSc student)
N. Kawal (MSc student)
A. Simo (MSc student)
J. Phulchand (MSc student, co-advised)