Dr. Marica Bakovic
Associate Professor
Email: mbakovic@uoguelph.ca
Office: ANNU 346
Ext: 53764
Lab: ANNU 309
Ext: 56717
Education | Research | Publications | Teaching | Grad Students |
Education
B.Sc. - Belgrade
M.Sc. - Belgrade
Ph.D. - Alberta
Research
Regulation of genes involved in choline transport and phospholipid metabolism; nutrient transporters and kinetics of membrane transport; molecular and cell biology of lipids; the effect of nutrients on protein synthesis and gene expression. Nutritional genomics (nutrigenomics) of risk factors for cardiovascular disease and insulin resistance
Selected Publications
Zhu, L. and Bakovic, M (2008) Liver X receptor agonists inhibit the phospholipid regulatory gene CTP:phosphoethanolamine cytidylyltransferase Pcyt2. Res. Lett. Biochem. Vol. 2008, ID 801849-5p.
Fullerton, M.D., Hakimuddin, F. and Bakovic, M. (2007) Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2). Mol Cell Biol 9: 3327-36.
Bakovic M, Fullerton MD and Michel V. (2007) Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2). Biochem Cell Biol. 85:283-300
Tie A and Bakovic M (2007) Alternative splicing of CTP: Phosphoethanolamine cytidylyltransferase produces two isoforms that differ in catalytic properties. J Lipid Res. 48(10):2172-81
Michel V and Bakovic M (2007) Lipid rafts in health and disease. Biol Cell 99:129-140
Fullerton MD , Wagner L., Yuan Z., & Bakovic M (2006) Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages. Am J Physiol Cell Physiol. 290(4):C1230-8.
Yuan Z., Tie A., Tarnopolski M., & Bakovic M (2006) Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1. Physiol Genomics, 26(1): 76-90.
Michel V., Yuan Z, Ramsubir S, & Bakovic M (2006) Choline transport for phospholipid synthesis. Exp Biol Med, 231(5): 490-504.
Teaching
HBNS*6440 Nutrition and Gene Expression
NUTR*4360 Current Issues in Nutrigenomics
Grad Students
K. Chiswell (MSc student)
B. Deschambault (PhD student)
J.P. Girardi (MSc student)
S. Guruge (MSc student)
V. Michel (PhD student)