All Services

Advanced Light Microscopy

Assisted or independent use of advanced light microscopes.

Facility: Molecular and Cellular Imaging

DNA Sequencing

Sample submission considerations.

The facility provides a number of standard sequencing primers for common plasmid vectors.
Custom primers should be provided at a concentration of 5 uM (=5 pmol/uL).

Request Forms:
Individual Sample Submissions
Sanger Sequencing Request - Use this form to submit DNA templates (ie. PCR amplicons, Plasmids, etc.) for sequencing
DIY Sequencing Request - Use this for to submit completed flourescent Sanger products (ie. BigDye reactions) for sequencing

For full and half-plate submissions please contact the facility

Equipment Used: Applied Biosystems 3730 DNA analyzer

Facility: Genomics

Electron Microscopy

Assisted or independent use of electron microscopes.

Facility: Molecular and Cellular Imaging

Fragment Analysis

Image Processing

  • LASAF - Leica Application Software Advanced Fluorescence
  • Volocity
  • Metamorph
  • NIS Elements
  • Zen 2.6 Blue
  • Amira
  • Imod

Facility: Molecular and Cellular Imaging

Large Molecule - MW Determination

MW determination for Proteins with desalting column.

Submission form for Protein MW

Equipment Used: Agilent LC-UHD Q-Tof

Facility: Mass Spectrometry

Large Molecule - Protein ID

Tryptic digest followed by MS analysis and database search using PEAKS 8 software.

Submission form for Protein ID

Equipment Used: Agilent LC-UHD Q-Tof

Facility: Mass Spectrometry

Next Generation Sequencing using MiSeq desktop sequencer

  • Metagenomics
  • Small genome sequencing
  • Amplicon sequencing
  • Targeted gene sequencing

Equipment Used: Illumina MiSeq Sequencer

Facility: Genomics

NMR Services

We are pleased to offer our NMR services to industrial, governmental, and academic users across North America. With 7 spectrometers and over 30 probes, we can collect spectra on virtually any NMR-active nuclide, in either the solution or solid state. Some examples of our services include:

  • Routine NMR spectra of small molecules in solution (e.g. 1D, COSY, NOESY, HSQC, HMBC, etc.)
  • 19F spectra, using a dedicated probe capable of simultaneous 1H decoupling
  • Variable temperature NMR spectra, with sample temperatures ranging from -20 C to 120 C.
  • Solution NMR spectra of metabolomics samples or other bio-materials, with optional solvent suppression
  • Solid-state NMR spectra of chemicals, materials, and biomolecules (e.g. static, magic-angle-spinning, cross-polarization)

The list above is by no means exhaustive! Please contact us if there is an experiment you are interested in. 

For routine NMR of small molecules, we suggest a concentration of 2 mg/mL for 1H experiments  and 20 mg/mL for 13C experiments. If sample limitations are a concern, our high-sensitivity cryoprobes can collect 1H NMR spectra on 0.1 mg/mL samples in a reasonable amount of time. 

Our service includes the raw NMR spectral data for processing on your computers, and we can also provide PDF spectral images for quick viewing of spectra. Routine NMR spectra are typically completed within two business days, and we accommodate "rush" service requests whenever possible. We can also offer data interpretation and analysis. Please contact the facility manager, Dr. Sameer Al-Abdul-Wahid, with enquires. 

Facility: NMR Centre