Mass Spectrometry Services
Large Molecule - MW Determination
MW determination for Proteins with desalting column.
Submission form for Protein MW
Equipment Used: Agilent LC-UHD Q-Tof
Large Molecule - Protein ID
Tryptic digest followed by MS analysis and database search using PEAKS 8 software.
Submission form for Protein ID
Equipment Used: Agilent LC-UHD Q-Tof
Small Molecule - Gas Chromatography Mass Spectrometry
GC-MS is used to analyze small molecules which are volatile or semi-volatile. Samples can be derivitized to improve volatility.
Useful article about sample preparation from Agilent Technologies.
Equipment Used: Agilent GC-MS, Bruker GC Scion TQ
Small Molecule - Liquid Chromatography Mass Spectrometry
LC-MS can be used to profile, identify and quantitate small molecules from a mixture.
Useful article about sample preparation from Agilent Technologies.
Submission form for high resolution LC-MS
Submission form for low resolution LC-MS or infusion
Equipment Used: Agilent LC-UHD Q-Tof
Small Molecule - Metabolomics (consult facility)
Refer to Metabolomics (2015) 11:851–860 for experimental design
Software Used: Agilent Mass Profiler Professional
Submission form for metabolomics
Equipment Used: Agilent LC-UHD Q-Tof