MCB Seminar Series: Dr. Jean-Philippe Julien
Date and Time
Please join us as we welcome Dr. Jean-Philippe Julien as part of MCB's Seminar Speaker Series on Wednesday, March 4th, 2020.
Seminar time: 10:30 - 11:30 AM
Room: SSC 2315
All are welcome to attend. Please see poster for further details.
MCB Distinguished Speaker Seminar Committee
Molecular characterization of antibodies to guide the development of next-generation malaria interventions
Our research focuses on characterizing protective antibodies of high potency against malaria antigens at the two bottlenecks of transmission between the mosquito vector and human host. Particularly, we use reverse vaccinology as an overarching approach to guide the design of novel immunogens for the development of an effective malaria vaccine. This concept is based on interrogating B cell repertoires of humans living in malaria endemic areas or partaking in clinical trials that evaluate emerging vaccine candidates. Our molecular studies uncover inhibitory antibodies that target sites of vulnerability on Plasmodium parasites. These findings have direct implications for the development of biomedical interventions against malaria, including novel vaccine candidates and antibody prophylactics.