MSc position to study the relationship between host genetics and pig gut microbiome
Dr. Brandon Lillie (Pathobiology), Dr. Khurram Nadeem (Mathematics and Statistics), Dr. Vahab Farzan (Pathobiology and Population Medicine)
PROJECT DESCRIPTION: The microbial colonization of the neonatal and adult gut plays a key role in function of immunological and metabolic pathways that influence disease resistance, health, and performance of pigs. Indeed, the mechanism-of-action of many commercially available intervention strategies and products designed to promote health and performance in pigs and replace antibiotics, is associated with their demonstrated ability to modify the composition of the gut microbiome. The application of molecular and bioinformatics methods has demonstrated that the gut microbiome is abundant, complex, and highly dynamic, partly influenced by host genetics. The overall goal of this MSc project is to investigate the relationship between host genetics and the swine gut microbiome. The project is specifically aiming to identify the single nucleotide variants with known roles in innate immunity and host resistance to microbes, as well as SNPs spaced across the entire genome, using a genome wide association study (GWAS) approach.
JOB DESCRIPTION: The successful candidate will develop and utilize bioinformatics pipelines to model various outcomes related to microbiome (Ex. alpha and beta diversity, microbiome composition) against single nucleotide variants through statistical modeling and genome wide association study.
Selection of the successful candidate is based on a combination of academic criteria, relevant experience, and referees’ evaluations. Previous experience in programming (e.g., R or Python) and knowledge of statistical methods such as regression analysis will be considered an asset. Review of applications will begin immediately and continue until the position is filled. The interested candidates should send a CV, a copy of undergraduate transcripts, a code example, a writing sample, names of three references, and a cover letter stating interest in the above-mentioned research topic to Dr. Vahab Farzan at firstname.lastname@example.org.
The University of Guelph is committed to an Employment Equity Program that includes special measures to achieve diversity among its faculty and staff. We therefore particularly encourage applications from members of underrepresented groups.
Gaze Tracking: MSc/Ph.D. student(s) projects related to eye tracking analytics and computational modelling
Dr. Maz Fallah (Human Health & Nutritional Sciences)
POSITION DESCRIPTION: They say the eyes are a window to our souls. We continue to show how the eyes intrinsically reflect other brain functions. To this end, we are seeking a strong and independent graduate student to study how eye movements reflect underlying cognitive and perceptual processing, in health and disease. The candidate will investigate how gaze reflects feature- and object-based visual processing, decision-making, target selection, and cognitive strategies. The research involves designing experiments using infrared eye trackers, analyzing gaze metrics (e.g. saccadic reaction times, trajectories, end-point deviations, etc), advancing computational models, and potentially developing neural network models. The successful candidate will have a relevant background (e.g. neuroscience, informatics, psychology, cognitive science, etc) and programming skills (preference for Matlab).
Relevant recent papers in this area include: Oculomotor target selection is mediated by complex objects Gaze patterns during presentation of fixed and random phase radial frequency patterns Perceptual color space representations in the oculomotor system are modulated by surround suppression and biased selection
HOW TO APPLY: All interested MSc candidates need to send a letter of interest, a CV, a copy of university transcripts, a code example, and the name/email address of a referee to: email@example.com. All interested PhD candidates need to send a letter of interest, a CV, a copy of university transcripts, a code example, a writing sample (such as a publication, MSc thesis chapter, or other project), and the names and email addresses of two referees to: firstname.lastname@example.org. Due to funding constraints, preference will be given to citizens and permanent residents of Canada.
The University of Guelph is committed to equity in its policies, practices, and programs, supports diversity in its teaching, learning and work environments, and ensures that applications from members of underrepresented groups are seriously considered under its employment equity policy. All qualified individuals who would contribute to the further diversification of our University community are encouraged to apply.
Browse previous M.Sc./Ph.D. opportunities that have been filled.