Cortland Griswold

Associate Professor
Phone number: 
519-824-4120 x56240
SSC 1474
  • B.Sc. – University of Wisconsin-Madison
  • M.Sc. – University of Toronto
  • Ph.D. – University of British Columbia

Theoretical Evolutionary Genetics

  • Ancestral graph theory
  • Polyploid population genetics
  • Prokaryotic population genetics
  • Metagenomic theory
  • Integrating theory and computational architecture

More recent representative papers

  • Verweij, W. and C.K. Griswold. 2023. Spatial structure and benefits to hosts allow plasmids with and without post-segregational killing systems to coexist. Biology Letters 19: 20220376.
  • Griswold, C.K and S. Asif. 2023. Meiosis at three loci in autotetraploids: Probabilities of gamete modes and genotypes without and with preferential cross-over formation.  Heredity 130: 223-235.
  • Griswold, C.K. 2022. A dynamic ancestral graph model and GPU-based simulation of a community based on metagenomic sampling. Molecular Ecology Resources 22: 2429 - 2442.
  • Griswold, C.K. 2021. The effects of migration load, selfing, inbreeding depression, and the genetics of adaptation on autotetraploid versus diploid establishment in peripheral habitats.  Evolution 75: 39-55.
  • Mostafaee, M. and C.K. Griswold. 2019. Two-Locus Local Adaptation by Additive or Epistatic Gene Combinations in Autotetraploids Versus Diploids. Journal of Heredity 110: 866-879.
  • Griswold, C.K. 2019. Properties of Samples With Segregating Polymerase Chain Reaction (PCR) Dropout Mutations Within a Species. Evolutionary Bioinformatics 15: 1-15.
  • Griswold, C.K. 2019. An ancestral process with selection in an ecological community.  Journal of Theoretical Biology 466: 128 - 144.
  • Griswold, C.K. and M.W. Williamson. 2017.  A two-locus model of selection in autotetraploids: Chromosomal gametic disequilibrium and selection for an adaptive epistatic gene combination.  Heredity 119: 314-327.

Earlier representative papers

  • Griswold, C.K.  2015.  Additive genetic variation and evolvability of a multivariate trait can be increased by epistatic gene action.  Journal of Theoretical Biology 387: 241-257.
  • Griswold, C.K.  2015.  Epistasis can accelerate adaptive diversification in haploid asexual populations.  Proceedings of the Royal Society B 282: 20142648.
  • McKay, P.B. and C.K. Griswold.  2014. A comparative study indicates both positive and purifying selection within ryanodine receptor (RyR) genes, as well as correlated evolution.  Journal of Experimental Zoology Part A: Ecological Genetics & Physiology 321: 151-163.
  • Griswold, C.K. and T.A. Henry.  2012.  Epistasis can increase multivariate trait diversity in haploid non-recombining populations.  Theoretical Population Biology 82: 209-221.
  • Griswold, C.K. and D.J. Eisner.  2012.  The mapping of epistatic effects onto a genealogical tree in haploid populations.  Theoretical Population Biology 81: 32-44.
  • Griswold, C.K. 2011. A Model of the Physiological Basis of a Multivariate Phenotype that is Mediated by Ca2+ Signaling and Controlled by Ryanodine Receptor Composition. Journal of Theoretical Biology 282: 14-22.
  • BIOL*2060 Ecology
  • BIOL*3020 Population Genetics
  • BIOL*3040 Methods in Evolutionary Biology
  • IBIO*6000/6070 Foundations in Theoretical Biology